Susaengrat W, Dhiensiri T, Sinavatana P, Sitprija V
Nephron. 1987;46(2):167-9. doi: 10.1159/000184334.
In a restrospective study of 220 patients with melioidosis admitted to the hospital over a period of 3.5 years, acute renal failure was noted in 77 patients. Interesting clinical features included hypercatabolism, hypoalbuminemia, hyponatremia, jaundice and multisystem involvement. Prognosis was poor especially when associated with jaundice, lung involvement and the presence of underlying diseases. Mortality rate was 89.6%. Renal failure is believed to the due to renal ischemia from multiple nonspecific factors. In a limited pathological study renal changes consisted of tubular necrosis, microabscesses, interstitial nephritis and mild tubular degeneration.
在一项对3.5年间收治入院的220例类鼻疽患者的回顾性研究中，77例患者出现急性肾衰竭。有趣的临床特征包括高分解代谢、低白蛋白血症、低钠血症、黄疸和多系统受累。预后较差，尤其是伴有黄疸、肺部受累和存在基础疾病时。死亡率为89.6%。肾衰竭被认为是由多种非特异性因素导致的肾缺血所致。在一项有限的病理学研究中，肾脏变化包括肾小管坏死、微脓肿、间质性肾炎和轻度肾小管变性。
