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小儿尿路感染的管理:一项德尔菲研究。

Management of Pediatric Urinary Tract Infections: A Delphi Study.

作者信息

Autore Giovanni, Bernardi Luca, La Scola Claudio, Ghidini Filippo, Marchetti Federico, Pasini Andrea, Pierantoni Luca, Castellini Claudia, Gatti Claudia, Malaventura Cristina, Pelusi Gabriella, Antodaro Francesco, Bergomi Andrea, Mazzini Franco, Parente Giovanni, Pillon Roberto, Cusenza Francesca, Biasucci Giacomo, De Fanti Alessandro, Iughetti Lorenzo, Perrone Serafina, Pession Andrea, Lima Mario, Esposito Susanna

机构信息

Pediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.

Pediatric Clinic, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.

出版信息

Antibiotics (Basel). 2022 Aug 18;11(8):1122. doi: 10.3390/antibiotics11081122.

DOI:10.3390/antibiotics11081122
PMID:36009990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9404756/
Abstract

Urinary tract infection (UTI) is one of the most common infectious diseases in the pediatric population and represents a major cause of antibiotic consumption and hospitalization in children. Considering the ongoing controversies on the management of pediatric UTI and the challenges due to increasing antimicrobial resistance, the aim of the present study was to evaluate the level of agreement on UTI management in pediatric age in Emilia-Romagna Region, Italy, and to assess on the basis of recent studies whether there is the need to change current recommendations used by primary care pediatricians, hospital pediatricians, and pediatric surgeons in everyday clinical practice to possibly improve outcomes. This consensus provides clear and shared indications on UTI management in pediatric age, based on the most updated literature. This work represents, in our opinion, the most complete and up-to-date collection of statements on procedures to follow for pediatric UTI, in order to guide physicians in the management of the patient, standardize approaches, and avoid abuse and misuse of antibiotics. Undoubtedly, more randomized and controlled trials are needed in the pediatric population to better define the best therapeutic management in cases with antimicrobial resistance and real usefulness of long-term antibiotic prophylaxis.

摘要

尿路感染(UTI)是儿科人群中最常见的传染病之一,也是儿童抗生素使用和住院的主要原因。鉴于儿科UTI管理方面持续存在的争议以及抗菌药物耐药性增加带来的挑战,本研究的目的是评估意大利艾米利亚 - 罗马涅地区儿科UTI管理的共识水平,并根据近期研究评估是否有必要改变初级保健儿科医生、医院儿科医生和儿科外科医生在日常临床实践中使用的当前建议,以可能改善治疗结果。本共识基于最新文献,就儿科UTI管理提供了明确且共同认可的指征。我们认为,这项工作是关于儿科UTI应遵循程序的最完整、最新的声明集合,旨在指导医生管理患者、规范治疗方法并避免抗生素的滥用和误用。毫无疑问,儿科人群需要更多随机对照试验,以更好地确定抗菌药物耐药情况下的最佳治疗管理以及长期抗生素预防的实际效用。

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Antibiotics (Basel). 2022 Feb 23;11(3):296. doi: 10.3390/antibiotics11030296.
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Children (Basel). 2022 Jan 19;9(2):128. doi: 10.3390/children9020128.
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J Glob Antimicrob Resist. 2022 Jun;29:499-506. doi: 10.1016/j.jgar.2021.11.003. Epub 2021 Nov 18.
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