胶质母细胞瘤免疫治疗的下一步措施
Next Steps for Immunotherapy in Glioblastoma.
作者信息
Cao Toni Q, Wainwright Derek A, Lee-Chang Catalina, Miska Jason, Sonabend Adam M, Heimberger Amy B, Lukas Rimas V
机构信息
Department of Neurology, Northwestern University, Chicago, IL 60611, USA.
Department of Neurological Surgery, Northwestern University, Chicago, IL 60611, USA.
出版信息
Cancers (Basel). 2022 Aug 20;14(16):4023. doi: 10.3390/cancers14164023.
Outcomes for glioblastoma (GBM) patients undergoing standard of care treatment remain poor. Here we discuss the portfolio of previously investigated immunotherapies for glioblastoma, including vaccine therapy and checkpoint inhibitors, as well as novel emerging therapeutic approaches. In addition, we explore the factors that potentially influence response to immunotherapy, which should be considered in future research aimed at improving immunotherapy efficacy.
接受标准治疗的胶质母细胞瘤（GBM）患者的预后仍然很差。在此，我们讨论了先前研究过的用于胶质母细胞瘤的免疫疗法组合，包括疫苗疗法和检查点抑制剂，以及新兴的治疗方法。此外，我们探讨了可能影响免疫治疗反应的因素，在未来旨在提高免疫治疗疗效的研究中应考虑这些因素。
Zotero 插件