Verheul Lisa M, Groeneveld Sanne A, Kirkels Feddo P, Volders Paul G A, Teske Arco J, Cramer Maarten J, Guglielmo Marco, Hassink Rutger J
Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Department of Cardiology, Maastricht University Medical Center, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands.
J Clin Med. 2022 Aug 10;11(16):4680. doi: 10.3390/jcm11164680.
Idiopathic ventricular fibrillation is a rare cause of sudden cardiac arrest and a diagnosis by exclusion. Unraveling the mechanism of ventricular fibrillation is important for targeted management, and potentially for initiating family screening. Sudden cardiac arrest survivors undergo extensive clinical testing, with a growing role for multimodality imaging, before diagnosing "idiopathic" ventricular fibrillation. Multimodality imaging, considered as using multiple imaging modalities as diagnostics, is important for revealing structural myocardial abnormalities in patients with cardiac arrest. This review focuses on combining imaging modalities (echocardiography, cardiac magnetic resonance and computed tomography) and the electrocardiographic characterization of sudden cardiac arrest survivors and discusses the surplus value of multimodality imaging in the diagnostic routing of these patients. We focus on novel insights obtained through electrostructural and/or electromechanical imaging in apparently idiopathic ventricular fibrillation patients, with special attention to non-invasive electrocardiographic imaging.
特发性室颤是心脏性猝死的罕见原因，需排除其他病因后方可诊断。阐明室颤机制对于针对性治疗以及启动家族筛查可能具有重要意义。心脏性猝死幸存者在被诊断为“特发性”室颤之前，需接受广泛的临床检查，其中多模态成像的作用日益凸显。多模态成像被视为使用多种成像方式进行诊断，对于揭示心脏骤停患者的心肌结构异常至关重要。本综述聚焦于成像方式（超声心动图、心脏磁共振成像和计算机断层扫描）的联合应用以及心脏骤停幸存者的心电图特征，并探讨多模态成像在这些患者诊断流程中的附加价值。我们重点关注通过电结构和/或机电成像在看似特发性室颤患者中获得的新见解，尤其关注无创心电图成像。
