Della Posta Daniele, Branca Jacopo Junio Valerio, Guarnieri Giulia, Veltro Cristiana, Pacini Alessandra, Paternostro Ferdinando
Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy.
Life (Basel). 2022 Aug 3;12(8):1186. doi: 10.3390/life12081186.
For many years, anatomical studies have been conducted with a shattered view of the body. Although the study of the different apparatuses provides a systemic view of the human body, the reconstruction of the complex network of anatomical structures is crucial for the understanding of structural and functional integration.
We used network analysis to investigate the connection between the whole-body osteo-myofascial structures of the human musculoskeletal system.
The musculoskeletal network was performed using the aNETomy anatomical network with the implementation of the open-source software Cytoscape for data entry.
The initial graph was applied with a network consisting of 2298 body parts (nodes) and 7294 links, representing the musculoskeletal system. Considering the same weighted and unweighted osteo-myofascial network, a different distribution was obtained, suggesting both a topological organization and functional behavior of the network structure.
Overall, we provide a deeply detailed anatomical network map of the whole-body musculoskeletal system that can be a useful tool for the comprehensive understanding of every single structure within the complex morphological organization, which could be of particular interest in the study of rehabilitation of movement dysfunctions.
多年来，解剖学研究一直是以一种碎片化的视角来进行的。尽管对不同器官系统的研究能提供人体的整体视图，但重建解剖结构的复杂网络对于理解结构和功能整合至关重要。
我们使用网络分析来研究人体肌肉骨骼系统的全身骨-肌筋膜结构之间的联系。
利用aNETomy解剖网络并通过开源软件Cytoscape进行数据录入来构建肌肉骨骼网络。
最初的图形应用于一个由2298个身体部位（节点）和7294条连接组成的网络，该网络代表肌肉骨骼系统。考虑相同的加权和未加权骨-肌筋膜网络时，得到了不同的分布，这表明了网络结构的拓扑组织和功能行为。
总体而言，我们提供了一份全身肌肉骨骼系统的详细解剖网络图，它可作为一个有用的工具，用于全面理解复杂形态组织内的每一个结构，这在运动功能障碍康复研究中可能具有特别的意义。
