College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Molecules. 2022 Aug 22;27(16):5344. doi: 10.3390/molecules27165344.
The genus (Moraceae), recognized for its value in many Chinese traditional herbs, mainly includes (L.) L'Hér. ex Vent. (), Siebold (), and (Blanco) Bureau (). Hitherto, researchers have found 338 compounds isolated from , , and , which included flavonoids, polyphenols, phenylpropanoids, alkaloids, terpenoids, steroids, and others. Moreover, its active compounds and extracts have exhibited a variety of pharmacological effects such as antitumor, antioxidant, anti-inflammatory, antidiabetic, anti-obesity, antibacterial, and antiviral properties, and its use against skin wrinkles. In this review, the phytochemistry and pharmacology of are updated systematically, after its applications are first summarized. In addition, this review also discusses the limitations of investigations and the potential direction of . This review can help to further understand the phytochemistry, pharmacology, and other applications of , which paves the way for future research.
该属（桑科）因其在许多中国传统草药中的价值而受到认可，主要包括桑（Morus alba L.）、构树（Broussonetia papyrifera (L.) Vent.）和榕属（Ficus Linn.）。迄今为止，研究人员已经从桑、构树和榕属中分离出 338 种化合物，其中包括黄酮类、多酚类、苯丙素类、生物碱类、萜类、甾体类等。此外，其活性化合物和提取物表现出多种药理作用，如抗肿瘤、抗氧化、抗炎、抗糖尿病、抗肥胖、抗菌和抗病毒特性，以及对皮肤皱纹的作用。在本综述中，在首先总结其应用后，系统地更新了桑属的植物化学和药理学。此外，本综述还讨论了研究的局限性和的潜在方向。本综述可以帮助进一步了解桑属的植物化学、药理学和其他应用，为未来的研究铺平道路。
