Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai, China.
Phytother Res. 2012 Jan;26(1):1-10. doi: 10.1002/ptr.3575. Epub 2011 Aug 31.
Plants belonging to the genus Broussonetia (Moraceae), which grow naturally in Asian and Pacific countries, have long been used in traditional Chinese medicine to treat various conditions, particularly tinea, dysentery, hernia and oedema. Various parts of plants of this genus such as the fruits, bark, leaves, flowers and roots are used medicinally. According to Flora of China, the inner bark fibre is used in making paper, and the wood is used for furniture. Several active compounds including coumarins, polyphenols, alkaloids, flavonoids, glycosides, lignans and diterpenes have been isolated from the plants of this genus in the past few years, and some members of these constituents have been demonstrated to exert antioxidant, antiinflammatory, antiplatelet, antityrosinase, antimicrobial and antinociceptive effects. Antidiabetic and antitumoural properties seem possible, but need further support. Due to the lack of clinical trials, there are few published reports on target-organ toxicity or side effects. Currently, some East Asian nations such as China, South Korea and Japan have shown increased interest in these plants. This article reviews the phytochemical and potential beneficial therapeutic effects of plants of this genus reported since 2000.
属于桑科榕属（Moraceae）的植物，自然生长在亚洲和太平洋国家，长期以来一直被用于中药治疗各种疾病，特别是癣、痢疾、疝气和水肿。该属植物的各种部位，如果实、树皮、叶子、花和根，都被药用。根据《中国植物志》，内树皮纤维用于造纸，木材用于制作家具。过去几年，从该属植物中分离出了多种活性化合物，包括香豆素、多酚、生物碱、类黄酮、糖苷、木脂素和二萜，其中一些成分已被证明具有抗氧化、抗炎、抗血小板、抗酪氨酸酶、抗菌和镇痛作用。抗糖尿病和抗肿瘤特性似乎是可能的，但需要进一步的支持。由于缺乏临床试验，关于这些植物的靶器官毒性或副作用的报道很少。目前，一些东亚国家，如中国、韩国和日本，对这些植物表现出了更大的兴趣。本文综述了自 2000 年以来报道的该属植物的植物化学和潜在有益的治疗作用。
