Carmona-Fonseca Jaime, Olivera Mario J, Yasnot-Acosta María F
Grupo Salud y Comunidad-Cesar Uribe Piedrahíta, Facultad de Medicina, Universidad de Antioquia, Medellín 050010, Colombia.
Instituto Nacional de Salud, Bogotá D.C. 111321, Colombia.
Pathogens. 2022 Aug 9;11(8):893. doi: 10.3390/pathogens11080893.
Knowledge of severe malaria (SM) or complicated malaria is insufficient in all its components. The least known type is the one associated with , compared to that caused by . The aim of this study was to provide a general overview of epidemiological information about the burden of SM, obtained from the National Public Health Surveillance System (SIVIGILA) for the period 2007-2020 in Colombia.
A descriptive, retrospective, and cross-sectional study of secondary information was performed via SIVIGILA.
There were 9881 SM cases among 1,060,950 total malaria cases in Colombia in 2007-2020: 9.31 SM cases per 1000 malaria cases. During this period, there were 7145 SM cases due to the following species: , 57.6%; , 38.6%; severe mixed malaria, 3.2%; and , 0.6%. The most compromised organ systems are the hematological system (54.9%), the liver (9.1%), the kidneys (4.2%), the lungs (1.9%) and the brain (1.6%).
There has been a reduction in malaria incidence in Colombia in the last 10-15 years, but there has also been a strong increase in SM incidence. We suggest emphasizing the prevention of the onset of severe malaria, with the early and accurate diagnosis of plasmodial infection.
人们对重症疟疾（SM）或复杂性疟疾的所有组成部分的了解都不够充分。与由[未提及的病原体]引起的疟疾相比，最不为人所知的类型是与[未提及的病原体]相关的那种。本研究的目的是概述从2007年至2020年期间哥伦比亚国家公共卫生监测系统（SIVIGILA）获得的关于重症疟疾负担的流行病学信息。
通过SIVIGILA对二手信息进行了描述性、回顾性和横断面研究。
2007年至2020年期间，哥伦比亚1,060,950例疟疾病例中共有9881例重症疟疾病例：每1000例疟疾病例中有9.31例重症疟疾病例。在此期间，有7145例重症疟疾病例由以下疟原虫种类引起：[未提及的疟原虫种类]，占57.6%；[未提及的疟原虫种类]，占38.6%；重症混合疟疾，占3.2%；以及[未提及的疟原虫种类]，占0.6%。受影响最严重的器官系统是血液系统（54.9%）、肝脏（9.1%）、肾脏（4.2%）、肺部（1.9%）和大脑（1.6%）。
在过去10至15年中，哥伦比亚的疟疾发病率有所下降，但重症疟疾的发病率也大幅上升。我们建议强调预防重症疟疾的发生，对疟原虫感染进行早期准确诊断。
