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纳米胶束在提高生物活性营养素的生物利用度和生物学功效方面的应用。

Application of Nanomicelles in Enhancing Bioavailability and Biological Efficacy of Bioactive Nutrients.

作者信息

Li Lei, Zeng Yun, Chen Minyi, Liu Gang

机构信息

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, China.

Department of Pharmacy, Xiamen Medical College, Xiamen 361023, China.

出版信息

Polymers (Basel). 2022 Aug 11;14(16):3278. doi: 10.3390/polym14163278.

Abstract

Nutraceuticals provide many biological benefits besides their basic nutritional value. However, their biological efficacies are often limited by poor absorption and low bioavailability. Nanomaterials have received much attention as potential delivery systems of nutrients and phytonutrients for multiple applications. Nanomicelles are nanosized colloidal structures with a hydrophobic core and hydrophilic shell. Due to their unique characteristics, they have shown great perspectives in food and nutraceutical science. In this review, we discussed the unique properties of nanomicelles. We also emphasized the latest advances on the design of different nanomicelles for efficient delivery and improved bioavailability of various nutrients. The role of nanomicelles in the efficacy improvement of bioactive components from nutraceutical and health foods has been included. Importantly, the safety concerns on nano-processed food products were highlighted.

摘要

营养保健品除了具有基本营养价值外,还具有许多生物学益处。然而,它们的生物学功效常常受到吸收不良和生物利用度低的限制。纳米材料作为营养物质和植物营养素的潜在递送系统在多种应用中受到了广泛关注。纳米胶束是具有疏水核心和亲水外壳的纳米级胶体结构。由于其独特的特性,它们在食品和营养保健品科学领域展现出了巨大的前景。在这篇综述中,我们讨论了纳米胶束的独特性质。我们还强调了不同纳米胶束设计方面的最新进展,以实现各种营养物质的高效递送和提高生物利用度。纳米胶束在营养保健品和健康食品中生物活性成分功效提升方面的作用也已涵盖。重要的是,突出了对纳米加工食品的安全担忧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f66/9415603/e8fc556323ab/polymers-14-03278-g001.jpg

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