Endodontic Section, Department of Stomatology, School of Dentistry, University of Sevilla, Sevilla, Spain.
Int Endod J. 2022 Nov;55(11):1105-1127. doi: 10.1111/iej.13822. Epub 2022 Sep 8.
The prevalence of root filled teeth (RFT) worldwide will inform about the amount of clinical activity of dentists dedicated to treat endodontic disease.
To carry out a systematic review with meta-analysis answering the following question: What is the prevalence of RFT around the world? The percentage of people with at least one RFT was also investigated.
A systematic review including population-based studies using the following databases: PubMed, EMBASE and Scielo. Studies related to prevalence of RFT were included. The outcome of interest of the study was the prevalence of RFT. The meta-analyses were calculated with the Open Meta Analyst software to determine the global prevalence of RFT. Subgroups analyses were performed comparing geographical distribution, radiographic method and year of the study (classified in 20th or 21th century). The prevalence of people with at least one RFT was also analysed.
Seventy-four population-based studies fulfilled the inclusion criteria. Twenty-eight, forty-four and two studies reported high, moderate and low risk of bias, respectively. No obvious publication bias was observed. Prevalence of RFT was estimated with 1 201 255 teeth and 32 162 patients. The calculated worldwide prevalence of RFT was 8.2% (95% CI = 7.3%-9.1%; p < .001). The global prevalence of people with at least one RFT was 55.7% (95% CI = 49.6%-61.8%; p < .001). In 20th century, the prevalence of RFT was 10.2% (95% CI = 7.9%-12.5%; p < .001), whereas in the 21st century the overall calculated prevalence of RFT was 7.5% (95% CI = 6.5%-8.6%; p < .001). Brazilian people (12%) and the European population (9.3%) showed the highest prevalence of RFT. In Europe, 59.6% (95% CI = 52.4%-66.8%) of people has at least one RFT.
This review showed that root canal treatment is a very common therapy throughout the world. More than half of the studied population have at least one RFT. A limitation of the present study is that most of the studies did not consider random sampling for population selection.
PROSPERO Systematic review registration number: (CRD42022329053).
全球范围内根管治疗牙（RFT）的流行情况将反映牙医治疗牙髓疾病的临床活动量。
进行系统评价和荟萃分析，回答以下问题：全球范围内 RFT 的流行情况如何？还调查了至少有一颗 RFT 的人的百分比。
系统评价纳入了基于人群的研究，使用了以下数据库：PubMed、EMBASE 和 Scielo。纳入了与 RFT 流行情况相关的研究。研究的兴趣结局是 RFT 的流行情况。使用 Open Meta Analyst 软件计算荟萃分析，以确定全球 RFT 的流行情况。进行了亚组分析，比较了地理位置分布、放射学方法和研究年份（分为 20 世纪或 21 世纪）。还分析了至少有一颗 RFT 的人的流行情况。
74 项基于人群的研究符合纳入标准。28、44 和 2 项研究分别报告了高、中、低偏倚风险。未观察到明显的发表偏倚。使用 1 201 255 颗牙齿和 32 162 名患者估计了 RFT 的全球流行率。计算得出的全球 RFT 流行率为 8.2%（95%CI=7.3%-9.1%；p<.001）。全球至少有一颗 RFT 的人的流行率为 55.7%（95%CI=49.6%-61.8%；p<.001）。20 世纪 RFT 的流行率为 10.2%（95%CI=7.9%-12.5%；p<.001），而 21 世纪整体计算的 RFT 流行率为 7.5%（95%CI=6.5%-8.6%；p<.001）。巴西人（12%）和欧洲人口（9.3%）的 RFT 流行率最高。在欧洲，59.6%（95%CI=52.4%-66.8%）的人至少有一颗 RFT。
本综述表明，根管治疗是全世界非常常见的治疗方法。研究人群中有一半以上至少有一颗 RFT。本研究的一个局限性是，大多数研究没有考虑为人群选择进行随机抽样。
PROSPERO 系统评价注册编号：（CRD42022329053）。
