Liu Jing-Chen, Zhang Chun-Li, Dong Kai-Ye, Li Ming-Jun, Sun Shu-Guang, Li Cai-Rui
Department of Ophthalmology, Jiangxi Provincial Hospital of Integrated Traditional Chinese and Western Medicine, the Fourth Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330003, Jiangxi Province, China.
School of Clinical Medicine, Dali University, Dali 671000, Yunnan Province, China.
Int J Ophthalmol. 2022 Aug 18;15(8):1391-1400. doi: 10.18240/ijo.2022.08.24. eCollection 2022.
Retinoblastoma (RB) is a highly aggressive ocular tumor, and due to socioeconomic and medical constraints, many children receive treatment only in the metaphase and advanced clinical stages, resulting in high rates of blindness and disability. Although several approaches exist in the treatment of RB, some children with the disease do not have satisfactory results because of various factors. Plant-derived natural products have shown definite therapeutic effects in the treatment of various tumors and are also widely used in the study of RB. We review plant-derived natural products used in the study of anti-RB to provide ideas for the clinical application of these drugs and the development of new therapeutic drugs.
视网膜母细胞瘤（RB）是一种极具侵袭性的眼部肿瘤，由于社会经济和医疗限制，许多儿童仅在临床中期和晚期才接受治疗，导致失明和残疾率很高。尽管在RB的治疗中有多种方法，但由于各种因素，一些患有该疾病的儿童并未取得令人满意的治疗效果。植物源天然产物在各种肿瘤的治疗中已显示出确切的治疗效果，并且也广泛应用于RB的研究中。我们综述了用于抗RB研究的植物源天然产物，为这些药物的临床应用和新治疗药物的开发提供思路。
