University of Toronto, Sunnybrook Health Sciences Centre, Department of Ophthalmology & Vision Sciences, Toronto, Canada.
University of Toronto, Division of Neurology, Department of Medicine, Toronto, Canada.
Turk J Ophthalmol. 2022 Aug 25;52(4):291-294. doi: 10.4274/tjo.galenos.2022.13245.
Multiple sclerosis (MS) is a chronic disorder characterized by demyelination of the central nervous system. It often presents in women aged 18-35 with neurological symptoms such as visual loss, paresthesia, focal weakness, and ataxia. Demyelination in the brainstem can result in internuclear ophthalmoplegia causing binocular horizontal diplopia. Our report details a patient with horizontal diplopia from an isolated abducens (sixth) nerve palsy as the initial symptom of MS. While rare, this demonstrates the importance of including MS in the differential diagnosis for an isolated abducens nerve palsy, especially in younger patients with no known vascular risk factors.
多发性硬化症（MS）是一种中枢神经系统脱髓鞘疾病。它常发生于 18-35 岁的女性，表现为视力丧失、感觉异常、局灶性无力和共济失调等神经系统症状。脑干部位的脱髓鞘可能导致核间性眼肌麻痹，导致双眼水平复视。我们的报告详细介绍了一位患者，其孤立性展神经（第六对脑神经）麻痹为 MS 的首发症状，表现为水平复视。尽管罕见，但这表明在孤立性展神经麻痹的鉴别诊断中应考虑 MS，特别是对于无已知血管危险因素的年轻患者。
