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艾滋病毒与新冠病毒:两场大流行的故事

HIV and COVID-19: A Tale of Two Pandemics.

作者信息

Kurdekar Aditya, Verma Shruti, Venkataramaniah Kamisetti

机构信息

Department of Instrumentation and Applied Physics, Optics and Microfluidics Instrumentation, Indian Institute of Science, CV Raman Road, Bengaluru, Karnataka 560012, India.

Department of Organisational Behaviour and Human Resources, Indian Institute of Management Indore, Prabandh Shikhar, Rau - Pithampur Road, Indore, Madhya Pradesh 453556, India.

出版信息

Curr HIV Res. 2022;20(5):344-349. doi: 10.2174/1570162X20666220823110435.

DOI:10.2174/1570162X20666220823110435
PMID:36017832
Abstract

In the last 5 decades, we have witnessed two major pandemics, AIDS caused by the Human Immunodeficiency Virus (HIV) and the CoronaVirus Disease-19 (COVID-19) caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2). The emergence of COVID-19 has raised many concerns for researchers, doctors, patients, and other institutions associated with HIV. A lot of debate has persisted on clinical outcomes, the use of antiretrovirals, and vaccines on HIV patients infected with COVID-19. This note attempts to present different aspects of HIV and SARS-CoV-2 across themes like SARS-CoV-2 coinfections in people living with HIV, the psychological impact, treatments, vaccination, etc. We highlight how learnings from the COVID-19 pandemic can help us in tackling the HIV pandemic.

摘要

在过去的50年里,我们目睹了两次重大的全球大流行,即由人类免疫缺陷病毒(HIV)引起的艾滋病和由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的冠状病毒病-19(COVID-19)。COVID-19的出现引起了研究人员、医生、患者以及其他与HIV相关机构的诸多关注。对于感染COVID-19的HIV患者的临床结局、抗逆转录病毒药物的使用以及疫苗接种等问题,一直存在很多争论。本报告试图从HIV和SARS-CoV-2的不同方面展开阐述,涵盖诸如HIV感染者中的SARS-CoV-2合并感染、心理影响、治疗、疫苗接种等主题。我们强调从COVID-19大流行中汲取的经验教训如何能帮助我们应对HIV大流行。

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本文引用的文献

1
Safety and Immunogenicity of Inactivated COVID-19 Vaccines Among People Living with HIV in China.中国HIV感染者中新型冠状病毒灭活疫苗的安全性和免疫原性
Infect Drug Resist. 2022 Apr 21;15:2091-2100. doi: 10.2147/IDR.S353127. eCollection 2022.
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Effectiveness of mRNA-1273 against SARS-CoV-2 Omicron and Delta variants.mRNA-1273 对 SARS-CoV-2 奥密克戎和德尔塔变异株的有效性。
Nat Med. 2022 May;28(5):1063-1071. doi: 10.1038/s41591-022-01753-y. Epub 2022 Feb 21.
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Changes in Mental Health Among People with HIV During the COVID-19 Pandemic: Qualitative and Quantitative Perspectives.
在 COVID-19 大流行期间 HIV 感染者心理健康的变化:定性和定量视角。
AIDS Behav. 2022 Jun;26(6):1980-1991. doi: 10.1007/s10461-021-03547-8. Epub 2022 Jan 7.
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Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021.艾滋病治愈研究重点:2021年国际艾滋病学会全球科学战略
Nat Med. 2021 Dec;27(12):2085-2098. doi: 10.1038/s41591-021-01590-5. Epub 2021 Dec 1.
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Victories against AIDS have lessons for COVID-19.抗击艾滋病的胜利为抗击新冠疫情提供了经验教训。
Nature. 2021 Dec;600(7887):9. doi: 10.1038/d41586-021-03569-1.
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BJPsych Open. 2021 Nov 2;7(6):e201. doi: 10.1192/bjo.2021.1046. eCollection 2021 Nov.
8
Prioritise people with HIV for COVID-19 vaccination.将感染艾滋病毒的人列为新冠疫苗接种的优先对象。
Lancet HIV. 2021 Nov;8(11):e659. doi: 10.1016/S2352-3018(21)00278-2.
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Gastrointestinal manifestations of human immunodeficiency virus and coronavirus disease 2019: Understanding the intersecting regions between the two epidemics.人类免疫缺陷病毒和 2019 年冠状病毒病的胃肠道表现:了解这两种流行病的交叉区域。
Arab J Gastroenterol. 2021 Jun;22(2):75-87. doi: 10.1016/j.ajg.2021.05.014. Epub 2021 May 26.
10
Eliminating HIV reservoirs for a cure: the issue is in the tissue.消除 HIV 储库以实现治愈:问题在于组织。
Curr Opin HIV AIDS. 2021 Jul 1;16(4):200-208. doi: 10.1097/COH.0000000000000688.