COVID-19 相关风险分层在管理早产儿视网膜病变中的有效性及未来意义：印度双子城早产儿视网膜病变研究报告第 10 号。

Effectiveness and future implications of COVID-19-related risk stratification for managing retinopathy of prematurity: The Indian twin cities retinopathy of prematurity study report number 10.

机构信息

Anant Bajaj Retina Institute, Srimati Kanuri Santhamma Center for Vitreo Retinal Diseases, Kallam Anji Reddy Campus, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Anant Bajaj Retina Institute, Vitreoretinal and Uveitis Services, L V Prasad Eye Institute, MithuTulsiChanrai Campus, Bhubaneswar, India.

出版信息

Indian J Ophthalmol. 2022 Sep;70(9):3356-3361. doi: 10.4103/ijo.IJO_677_22.

DOI:10.4103/ijo.IJO_677_22

PMID:36018120

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9675525/

Abstract

PURPOSE

To evaluate the effectiveness and future implications of COVID-related risk stratification for managing retinopathy of prematurity (ROP).

METHODS

A prospective study was conducted at a tertiary eye care center from the beginning of the lockdown in India from 23 March 2020 till the end of the first phase of lockdown on 29 May 2020. We evaluated 200 prematurely born infants (< 34 weeks of gestational age) using the new safety guideline protocols for low-risk babies developed in conjunction with the Indian ROP Society for care during the COVID-19 pandemic. Low risk included babies born at more than 30 weeks of gestational age, post menstrual age 34 weeks or above at presentation, more than 1000 grams of birth weight, and stable systemically with good weight gain.

RESULTS

New guidelines were implemented in 106 (53%) infants who were low risk while 94 (47%) infants with high risk were followed up as per the old guidelines. Out of the 106 infants (212 eyes) managed by the new guidelines, good outcome (group 1) was seen in 102 (96.2%) infants. Twenty-seven of the 102 infants had some form of ROP and 5 of these infants needed treatment. None of the low-risk babies with no detachment at presentation managed by new guidelines required surgery later (group 2). Two (1.9%) infants came with retinal detachment at presentation and underwent successful surgery (group 3) and two infants (1.9%) were lost to follow up.

CONCLUSION

New risk stratification during the COVID-19 pandemic was an efficient and safe strategy in managing low-risk ROP babies.

摘要

目的

评估 COVID 相关风险分层在管理早产儿视网膜病变（ROP）中的有效性及对未来的影响。

方法

这是一项在印度封锁开始时（2020 年 3 月 23 日）至 2020 年 5 月 29 日封锁第一阶段结束时，在一家三级眼科保健中心进行的前瞻性研究。我们使用印度 ROP 学会联合制定的新的安全指南方案评估了 200 名早产儿（<34 周胎龄），该方案适用于在 COVID-19 大流行期间的护理。低危包括出生时胎龄超过 30 周、就诊时的月经龄超过 34 周、出生体重超过 1000 克、系统稳定且体重增加良好的婴儿。

结果

新指南在 106 名（53%）低危婴儿中得到实施，而 94 名（47%）高危婴儿则按照旧指南进行了随访。在按照新指南管理的 106 名婴儿（212 只眼）中，102 名（96.2%）出现良好结局（第 1 组）。在 102 名有某种形式 ROP 的婴儿中，27 名需要治疗。在新指南管理下，无脱离的低危婴儿在以后均无需手术（第 2 组）。2 名婴儿就诊时即出现视网膜脱离并成功接受手术（第 3 组），2 名婴儿失访。