Berg R W
Pediatrician. 1987;14 Suppl 1:27-33.
Common diaper dermatitis is an episodic disease that results from attack of the skin by physical, chemical, enzymatic, and microbial factors in the diaper environment. A model for the cyclic nature of this disease has been developed which incorporates various roles these factors play as they interact to produce skin with compromised physical properties, and further damage it to produce diaper dermatitis. Resolution occurs naturally or through caretaker intervention, resulting in mean episodic durations of 2-3 days. The model predicts that preventing excessive skin hydration, maintaining skin near its normal physiologic pH, and minimizing interaction of urine and feces (which increases pH and fecal enzyme activity) will result in decreased incidence and severity of diaper dermatitis.
常见尿布皮炎是一种发作性疾病,由尿布环境中的物理、化学、酶和微生物因素侵袭皮肤所致。针对这种疾病的周期性特点已建立了一个模型,该模型纳入了这些因素在相互作用时所起的各种作用,它们相互作用导致皮肤物理性质受损,并进一步对其造成损害,从而引发尿布皮炎。尿布皮炎自然消退或通过护理人员的干预而消退,平均发作持续时间为2 - 3天。该模型预测,防止皮肤过度水合、使皮肤维持在接近正常生理pH值的状态,以及尽量减少尿液和粪便的相互作用(尿液和粪便的相互作用会提高pH值并增加粪便酶活性),将降低尿布皮炎的发病率和严重程度。