Alessi N E, Robbins D R, Dilsaver S C
Psychiatry Res. 1987 Apr;20(4):275-83. doi: 10.1016/0165-1781(87)90088-6.
Sixty-one adolescents hospitalized on an inpatient psychiatric unit were evaluated to determine whether they met criteria for panic and affective disorders according to Research Diagnostic Criteria. Ten (16%) and 15 (24%) met criteria for definite or possible panic disorder. Fifteen (24.5%) had major depressive disorder (MDD) endogenous subtype, 10 (16%) had MDD nonendogenous subtype, 8 (13%) had minor depressive disorder (mDD), and 27 (44%) had no diagnosable mood disorder. Four adolescents with definite panic disorders were diagnosed as having MDD endogenous subtype, three MDD, two mDD, and one had no diagnosable depressive disorder. The mean total score on the Hamilton Rating Scale for Depression (HRSD) was significantly higher among those subjects with definite panic attacks compared with those with either possible or no panic. Patients with definite panic disorder showed significant increases on the HRSD items of guilt, decreased work and interest, psychological and somatic anxiety, and weight loss compared to these samples.
对61名住院精神科病房的青少年进行了评估，以根据研究诊断标准确定他们是否符合惊恐障碍和情感障碍的标准。10名（16%）和15名（24%）符合确诊或可能的惊恐障碍标准。15名（24.5%）患有内源性重度抑郁症（MDD）亚型，10名（16%）患有非内源性MDD亚型，8名（13%）患有轻度抑郁症（mDD），27名（44%）没有可诊断的情绪障碍。4名确诊惊恐障碍的青少年被诊断为患有内源性MDD亚型，3名患有MDD，2名患有mDD，1名没有可诊断的抑郁症。与那些可能有或没有惊恐发作的受试者相比，确诊惊恐发作的受试者在汉密尔顿抑郁量表（HRSD）上的平均总分显著更高。与这些样本相比，确诊惊恐障碍的患者在HRSD的内疚感、工作和兴趣下降、心理和躯体焦虑以及体重减轻等项目上有显著增加。
