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米安色林(ORG GB 94)与阿米替林治疗抑郁症的三项双盲对照试验。

Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness.

作者信息

Jaskari M O, Ahfors U G, Ginman L, Lydekcne K, Tienari P

出版信息

Pharmakopsychiatr Neuropsychopharmakol. 1977 Mar;10(2):101-3. doi: 10.1055/s-0028-1094526.

Abstract

The results of double-blind comparative trials carried out simultaneously in three Finnish hospitals are presented. The antidepressant activity and side-effects of mianserine (ORG GB 94) and amitriptyline were compared. No statistically significant differences were found between the two treatments. It was found, however, that mianserine had clearly less anticholinergic side-effects than amitriptyline.

摘要

本文展示了在芬兰三家医院同时进行的双盲对比试验结果。对米安色林(ORG GB 94)和阿米替林的抗抑郁活性及副作用进行了比较。两种治疗方法之间未发现具有统计学意义的差异。然而,发现米安色林的抗胆碱能副作用明显少于阿米替林。

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