米安色林在全科医疗中治疗抑郁性疾病和焦虑状态的应用
Mianserin in the treatment of depressive illness and anxiety states in general practice.
作者信息
Murphy J E
出版信息
Br J Clin Pharmacol. 1978;5 Suppl 1(Suppl 1):81S-85S.
Abstract
- In an initial study in general practice, mianserin was shown to be of similar antidepressant efficacy to imipramine. 2. A subsequent placebo-controlled study confirmed that mianserin is an effective as imipramine, and also demonstrated that both mianserin and imipramine are superior to placebo in the treatment of depression in general practice. 3. In a third trial, mianserin was found to be as effective as diazepam in the treatment of anxiety states in general practice. 4. The overall incidence of side-effects in this series of studies, either with mianserin or with the comparison drugs, was very low.
摘要
- 在一项普通医疗实践的初步研究中，米安色林显示出与丙咪嗪相似的抗抑郁疗效。2. 随后一项安慰剂对照研究证实，米安色林与丙咪嗪一样有效，并且还表明米安色林和丙咪嗪在普通医疗实践中治疗抑郁症方面均优于安慰剂。3. 在第三项试验中，发现在普通医疗实践中米安色林在治疗焦虑状态方面与地西泮一样有效。4. 在这一系列研究中，使用米安色林或对照药物的副作用总体发生率非常低。
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Mianserin in the treatment of depression in general practice.米安色林在全科医疗中治疗抑郁症的应用
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Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness.米安色林（ORG GB 94）与阿米替林治疗抑郁症的三项双盲对照试验。
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