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米安色林与阿米替林对比。一项由AMP系统评估的双盲试验。

Mianserin versus amitriptyline. A double-blind-trial evaluated by the AMP system.

作者信息

Vogel H P, Bente D, Feder J, Helmchen H, Müller-Oerlinghausen B, Bohacek N, Mihovilović M, Brändli A, Fleischhauer J, Walcher W

出版信息

Int Pharmacopsychiatry. 1976;11(1):25-31.

PMID:770364
Abstract

Amitriptyline and mianserin were compared in a double-blind trial. Most of the depressive symptoms were influenced by both drugs, though quantitative and qualitative differences became evident. Amitriptyline predominantly influenced anxiety, despair and suicidal tendencies, while mianserin was particularly effective in psychomotor inhibition and the reduction of vegitative complaints. Mianserin did not show anticholinergic side effects.

摘要

在一项双盲试验中对阿米替林和米安色林进行了比较。两种药物都对大多数抑郁症状有影响,不过在数量和质量上的差异变得明显起来。阿米替林主要影响焦虑、绝望和自杀倾向,而米安色林在精神运动抑制和减少植物神经紊乱症状方面特别有效。米安色林未表现出抗胆碱能副作用。

相似文献

1
Mianserin versus amitriptyline. A double-blind-trial evaluated by the AMP system.米安色林与阿米替林对比。一项由AMP系统评估的双盲试验。
Int Pharmacopsychiatry. 1976;11(1):25-31.
2
Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness.米安色林(ORG GB 94)与阿米替林治疗抑郁症的三项双盲对照试验。
Pharmakopsychiatr Neuropsychopharmakol. 1977 Mar;10(2):101-3. doi: 10.1055/s-0028-1094526.
3
Proceedings: Mianserin vs. amitriptyline--a double-blind-trial evaluated by the AMP-system.研究进展:米安色林与阿米替林对比——一项由AMP系统评估的双盲试验。
Act Nerv Super (Praha). 1975;17(4):229-30.
4
A double blind comparative study of mianserin and a fixed combination of amitriptyline plus chlordiazepoxide.
Adv Biochem Psychopharmacol. 1982;32:213-22.
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A comparison of the cardiac effects of mianserin and amitriptyline in man.米安色林与阿米替林对人体心脏影响的比较。
Pharmakopsychiatr Neuropsychopharmakol. 1977 Dec;10(6):309-12. doi: 10.1055/s-0028-1094554.
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Treatment of severe depressive illness: a double-blind comparison of mianserin and long-acting amitriptyline.重度抑郁症的治疗:米安色林与长效阿米替林的双盲对照研究
Br J Clin Pract. 1982 Jun;36(6):240-2.
7
Differential effects on suicidal ideation of mianserin, maprotiline and amitriptyline.米安色林、马普替林和阿米替林对自杀意念的不同影响。
Br J Clin Pharmacol. 1978;5 Suppl 1(Suppl 1):77S-80S.
8
A comparative clinical trial of mianserin (Norval) and amitriptyline in the treatment of depression in general practice.
J Int Med Res. 1978;6(3):199-206. doi: 10.1177/030006057800600306.
9
Mianserin in the treatment of depressive illness: a comparison with amitriptyline.
Ir J Med Sci. 1979 Apr;148(4):145-8.
10
A double-blind comparative trial with mianserin and amitriptyline in outpatients with major depressive disorders.米安色林与阿米替林治疗重度抑郁症门诊患者的双盲对照试验。
Br J Clin Pharmacol. 1983;15 Suppl 2(Suppl 2):227S-237S. doi: 10.1111/j.1365-2125.1983.tb05870.x.

引用本文的文献

1
Mianserin in the treatment of depressive illness: A comparison with amitriptyline.米安色林治疗抑郁症:与阿米替林的比较。
Ir J Med Sci. 1979 Dec;148(1):145. doi: 10.1007/BF02938068.
2
Amitriptyline for depression.用于治疗抑郁症的阿米替林。
Cochrane Database Syst Rev. 2007 Jul 18(3):CD004186. doi: 10.1002/14651858.CD004186.pub2.
3
A double-blind comparative trial with mianserin and amitriptyline in outpatients with major depressive disorders.米安色林与阿米替林治疗重度抑郁症门诊患者的双盲对照试验。
Br J Clin Pharmacol. 1983;15 Suppl 2(Suppl 2):227S-237S. doi: 10.1111/j.1365-2125.1983.tb05870.x.
4
Do some antidepressants promote suicide?
Psychopharmacology (Berl). 1987;92(2):265-6. doi: 10.1007/BF00177927.
5
Mianserin: a decade of scientific development.米安色林:十年科学发展历程
Br J Clin Pharmacol. 1978;5 Suppl 1(Suppl 1):5S-9S.
6
Uptake inhibition of biogenic amines by newer antidepressant drugs: relevance to the dopamine hypothesis of depression.新型抗抑郁药物对生物胺的摄取抑制作用:与抑郁症的多巴胺假说的相关性。
Psychopharmacology (Berl). 1977 Aug 16;53(3):309-14. doi: 10.1007/BF00492370.
7
Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.米安色林:其药理特性及对抑郁症治疗效果的综述
Drugs. 1978 Oct;16(4):273-301. doi: 10.2165/00003495-197816040-00001.
8
Anticholinergic and blood pressure effects of mianserin, amitriptyline and placebo.米安色林、阿米替林及安慰剂的抗胆碱能作用和血压影响
Br J Clin Pharmacol. 1978;5 Suppl 1(Suppl 1):29S-34S.