Widrich W C, Robbins A H, Goldstein S A, Singer R J
Radiology. 1978 Nov;129(2):371-3. doi: 10.1148/129.2.371.
It has been shown that lidocaine administered as a bolus intra-arterially immediately prior to contrast media injections significantly decreased the pain experienced from aortofemoral arteriography. Some researchers have advocated mixing 2 mgm of lidocaine with each ml of contrast agent rather than giving it as a bolus prior to the contrast agent. In a randomized study of 30 patients, the authors demonstrated that both methods are equally effective in decreasing the pain from aortofemoral arterography and that mixing the lidocaine with the contrast agent is the easier method.
研究表明,在注射造影剂之前立即经动脉推注利多卡因,可显著减轻主动脉股动脉造影术所致的疼痛。一些研究人员主张在每毫升造影剂中混合2毫克利多卡因,而不是在注射造影剂之前推注给药。在一项针对30名患者的随机研究中,作者证明这两种方法在减轻主动脉股动脉造影术疼痛方面同样有效,并且将利多卡因与造影剂混合使用更为简便。