The State Key Lab of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, People's Republic of China.
Department of Chemical Engineering and Key Laboratory of Advanced Materials of Ministry of Education, Tsinghua University, Beijing 100084, People's Republic of China.
Talanta. 2023 Jan 15;252:123849. doi: 10.1016/j.talanta.2022.123849. Epub 2022 Aug 23.
The development of cost-effective sensing system for Hg quantitation is highly demanded for environmental monitoring. In this work, we reported an on-site, rapid and portable smartphone-based Hg sensing system integrating coumarin-modified paper as a probe and smartphone readout device as a processing platform. For fluorescent sensing of Hg, the modified paper was fabricated by chemically grafting a coumarin-based probe N-((7-hydroxy-coumarin-3-yl)carbamothioyl)acetamide (HCCA) onto paper, and its physicochemical properties and sensing performance were characterized by elemental analysis, FTIR, XPS, SEM, and fluorescence spectral analysis. The modified paper displayed high selectivity and sensitivity for Hg, accompanied with a distinct fluorescence color change. For portable detection of the fluorescent sensors, a smartphone readout device was designed, consisting of a removable 3D-printed hardware device and an application. Remarkably, the smartphone readout device in cooperation with the modified paper is highly selective and sensitive to Hg with the limit of detection (LOD) of 0.46 ppb, which avoids the requirement of sophisticated equipment and complex operation. The cost-effective sensing system based on smartphone shows a great potential for monitoring of Hg in environmental water.
为了进行环境监测，人们对开发经济高效的汞定量传感系统提出了很高的要求。在这项工作中，我们报告了一种基于智能手机的现场、快速和便携式汞传感系统，该系统集成了香豆素修饰的纸张作为探针和智能手机读取设备作为处理平台。为了进行荧光传感，通过化学接枝将香豆素基探针 N-((7-羟基香豆素-3-基)氨甲酰硫基)乙酰胺 (HCCA) 接枝到纸张上，制备了修饰后的纸张，并通过元素分析、FTIR、XPS、SEM 和荧光光谱分析对其物理化学性质和传感性能进行了表征。修饰后的纸张对 Hg 表现出高选择性和灵敏度，同时伴随着明显的荧光颜色变化。为了对荧光传感器进行便携式检测，设计了一种智能手机读取设备，由可移动的 3D 打印硬件设备和应用程序组成。值得注意的是，智能手机读取设备与修饰后的纸张配合使用，对 Hg 具有高度选择性和灵敏度，检测限 (LOD) 低至 0.46 ppb，避免了对复杂设备和复杂操作的需求。基于智能手机的经济高效传感系统在环境水中监测 Hg 方面具有很大的潜力。
