Laboratory of Vision Sciences and Applications. Department of Optics. University of Granada. Av. Fuentenueva s/n. 18071. Granada, Spain.
Laboratory of Vision Sciences and Applications. Department of Optics. University of Granada. Av. Fuentenueva s/n. 18071. Granada, Spain.
Exp Eye Res. 2022 Nov;224:109231. doi: 10.1016/j.exer.2022.109231. Epub 2022 Aug 24.
This study aimed to assess and compare the influence of alcohol intake and cannabis smoking on different visual functions. A total of 64 young and healthy volunteers took part in the study. All undertook several randomised experimental sessions in which different visual functions, namely distance stereopsis, retinal straylight, visual discrimination capacity, and contrast sensitivity, were tested. Cannabis smokers (N = 30) took a baseline session and a session after smoking a cannabis cigarette, whereas alcohol users (N = 34) underwent a baseline session, a session after a low alcohol intake (Alcohol 1), and a session after a moderate to high alcohol intake (Alcohol 2). All visual functions were impaired by cannabis and alcohol use, particularly for the Cannabis and Alcohol 2 groups. The deterioration of all visual variables was higher for the Alcohol 2 than for the Alcohol 1 and Cannabis groups, except for retinal straylight, the deterioration of which was equal for the Cannabis group, and distant stereopsis, which was more impaired for the Cannabis group. The Alcohol 2 group experienced the most impairing conditions, although very similar to the cannabis group, and that factors other than the experimental conditions, such as sex and age, also influenced these visual changes. Alcohol and cannabis use clearly impair vision. The deterioration caused by cannabis is similar to, but slightly lower than, that produced by a moderate to high alcohol intake, with the experimental conditions, sex and age all having an impact on the variability of visual deterioration.
这项研究旨在评估和比较酒精摄入和大麻吸烟对不同视觉功能的影响。共有 64 名年轻健康的志愿者参与了这项研究。所有志愿者都参加了几次随机实验，在这些实验中测试了不同的视觉功能，包括远距离立体视、视网膜散射光、视觉辨别能力和对比敏感度。大麻吸烟者（N=30）进行了基线测试和吸烟大麻烟后的测试，而酒精使用者（N=34）则进行了基线测试、低酒精摄入后的测试（酒精 1）和中到高酒精摄入后的测试（酒精 2）。大麻和酒精的使用都损害了所有的视觉功能，尤其是大麻和酒精 2 组。除了视网膜散射光，酒精 2 组的所有视觉变量的恶化程度都高于酒精 1 组和大麻组，而视网膜散射光的恶化程度在大麻组中是相等的，远距离立体视在大麻组中受损更严重。酒精 2 组的情况最严重，尽管与大麻组非常相似，但实验条件、性别和年龄等其他因素也会影响这些视觉变化。酒精和大麻的使用显然会损害视力。大麻引起的恶化与中到高酒精摄入引起的恶化相似，但略低，实验条件、性别和年龄都会对视觉恶化的可变性产生影响。
