Human Sperm Bank, Zhejiang Mater Child and Reproductive Health Center, Hangzhou, Zhejiang, China.
School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
BMJ Open. 2022 Aug 26;12(8):e061354. doi: 10.1136/bmjopen-2022-061354.
This study aims to examine the association between occupational factors and semen quality in semen donors in eastern China.
We recruited 12 301 semen donors from 2006 to 2020 as the studying population. A self-designed questionnaire was applied for collecting lifestyle and work style information. Semen samples were analysed according to WHO guidelines. A crude and adjusted linear regression model was used to analyse the association between occupational factors and semen quality.
College students accounted for 36.2% of all semen donors. The majority (81.3%) of semen donors were between 18 year and 30 years. Soldiers or the police had the highest semen volume (the median value=3.8 mL), however, they had the lowest sperm concentration (53.6×10/ml) and sperm motility (45.5%). Workers in finance or insurance had an elevated risk of low semen volume, sperm concentration and total sperm count (=1.43, 1.57 and 1.98, respectively). Unemployed men had a high risk of low sperm concentration and low total sperm count (=1.84 and 1.58, respectively). Working in the information technology industry had a deleterious effect on the progressive motility of sperm (=1.27, 95% CI 1.03 to 1.57).
Our study indicated that sedentary work style and intensive sports in certain professions might be associated with decreased semen quality. We reported evidence of becoming unemployed on the damage to semen quality. Hence, we advocate a healthy work style to improve semen quality in eastern China.
本研究旨在探讨中国东部职业因素与精液质量的关系。
我们招募了 12301 名 2006 年至 2020 年的精液捐献者作为研究人群。采用自行设计的问卷收集生活方式和工作方式信息。根据世卫组织指南分析精液样本。采用粗线性和调整线性回归模型分析职业因素与精液质量的关系。
大学生占所有精液捐献者的 36.2%。大多数（81.3%）的精液捐献者年龄在 18 岁至 30 岁之间。军人或警察的精液量最高（中位数=3.8ml），但精子浓度（53.6×10/ml）和精子活力（45.5%）最低。金融或保险行业的劳动者精液量、精子浓度和总精子数偏低的风险较高（分别为 1.43、1.57 和 1.98）。失业男性精子浓度和总精子数偏低的风险较高（分别为 1.84 和 1.58）。从事信息技术行业对精子的前向运动能力有不良影响（分别为 1.27、95%CI1.03-1.57）。
本研究表明，某些职业的久坐工作方式和剧烈运动可能与精液质量下降有关。我们报告了失业对精液质量的损害的证据。因此，我们提倡健康的工作方式，以改善中国东部的精液质量。
