Inner Mongolia YiLi Industrial Group Co. Ltd., Hohhot, China 010110; Inner Mongolia Dairy Technology Research Institute Co. Ltd., Hohhot, China 010110.
Inner Mongolia YiLi Industrial Group Co. Ltd., Hohhot, China 010110; Inner Mongolia Dairy Technology Research Institute Co. Ltd., Hohhot, China 010110.
J Dairy Sci. 2022 Oct;105(10):7959-7971. doi: 10.3168/jds.2021-21127. Epub 2022 Aug 24.
Milk proteins have received much awareness due to their bioactivity. However, their encapsulation functions have not attracted enough attention. Milk proteins as encapsulation walls can increase the bioavailability of bioactive compounds. As the benefits of bioactive compounds are critically determined by bioavailability, the effect of interactions between milk proteins and active substances is a critical topic. In the present review, we summarize the effects of milk proteins as encapsulation walls on the bioavailability of active substances with a special focus. The methods and mechanisms of interactions between milk proteins and active substances are also discussed. The evidence collected in the present review suggests that when active substances are encapsulated by milk proteins, the bioavailability of active substances can be significantly affected. This review also provides valuable guidelines for the use of milk protein-based microcarriers.
由于其生物活性，乳蛋白受到了广泛关注。然而，其包封功能尚未引起足够重视。乳蛋白作为包封壁可以提高生物活性化合物的生物利用度。由于生物活性化合物的益处取决于其生物利用度，因此，乳蛋白与活性物质之间的相互作用的影响是一个关键的话题。在本综述中，我们特别总结了乳蛋白作为包封壁对活性物质生物利用度的影响。还讨论了乳蛋白与活性物质相互作用的方法和机制。本综述中收集的证据表明，当活性物质被乳蛋白包封时，活性物质的生物利用度会受到显著影响。本综述还为使用基于乳蛋白的微载体提供了有价值的指导。
