Suwanangul Saranya, Jaichakan Pannapapol, Narkprasom Nukrob, Kraithong Supaluck, Narkprasom Kanjana, Sangsawad Papungkorn
Program in Food Science and Technology, Faculty of Engineering and Agro-Industry, Maejo University, Chiang Mai 50290, Thailand.
Faculty of Business Administration, Chitralada Technology Institute, Bangkok 10300, Thailand.
Foods. 2023 Oct 8;12(19):3692. doi: 10.3390/foods12193692.
This study investigates the use of encapsulating agents for establishing a synbiotic relationship with (TISTR 1447). Various ratios of wall materials, such as skim milk powder, maltodextrin, and cellulose acetate phthalate (represented as SMC1, SMC3, SMC5, and SMC7), were examined. In all formulations, 5% inulin was included as a prebiotic. The research assessed their impact on cell viability and bioactive properties during both the spray-drying process and in vitro gastrointestinal digestion. The results demonstrate that these encapsulating agents efficiently protect spores during the spray-drying process, resulting in spore viability exceeding 6 log CFU/g. Notably, SMC5 and SMC7 displayed the highest spore viability values. Moreover, SMC5 showcased the most notable antioxidant activity, encompassing DPPH, hydroxy radical, and superoxide radical scavenging, as well as significant antidiabetic effects via the inhibition of α-amylase and α-glucosidase. Furthermore, during the simulated gastrointestinal digestion, both SMC5 and SMC7 exhibited a slight reduction in spore viability over the 6 h simulation. Consequently, SMC5 was identified as the optimal condition for synbiotic production, offering protection to spores during microencapsulation and gastrointestinal digestion while maintaining bioactive properties post-encapsulation. Synbiotic microcapsules containing SMC5 showcased a remarkable positive impact, suggesting its potential as an advanced food delivery system and a functional ingredient for various food products.
本研究调查了使用包囊剂与（TISTR 1447）建立合生元关系的情况。研究了各种比例的壁材，如脱脂奶粉、麦芽糊精和邻苯二甲酸醋酸纤维素（分别表示为SMC1、SMC3、SMC5和SMC7）。在所有配方中，均包含5%的菊粉作为益生元。该研究评估了它们在喷雾干燥过程和体外胃肠道消化过程中对细胞活力和生物活性特性的影响。结果表明，这些包囊剂在喷雾干燥过程中能有效保护芽孢，使芽孢活力超过6 log CFU/g。值得注意的是，SMC5和SMC7的芽孢活力值最高。此外，SMC5表现出最显著的抗氧化活性，包括清除DPPH、羟基自由基和超氧自由基，以及通过抑制α-淀粉酶和α-葡萄糖苷酶产生显著的抗糖尿病作用。此外，在模拟胃肠道消化过程中，SMC5和SMC7在6小时的模拟过程中芽孢活力均略有下降。因此，SMC5被确定为合生元生产的最佳条件，在微胶囊化和胃肠道消化过程中能保护芽孢，同时在包囊后保持生物活性特性。含有SMC5的合生元微胶囊显示出显著的积极影响，表明其作为先进食品递送系统和各种食品功能成分的潜力。
