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器官移植相关的费用:系统评价。

Costs related to obtaining organs for transplantation: A systematic review.

机构信息

Health and Development of the Midwest Region at the Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.

Graduate Program in Nursing, Integrated Health Institute, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.

出版信息

Transplant Rev (Orlando). 2022 Dec;36(4):100724. doi: 10.1016/j.trre.2022.100724. Epub 2022 Aug 19.

DOI:10.1016/j.trre.2022.100724
PMID:36029555
Abstract

INTRODUCTION

The number of transplants in the world is growing, although there is a demand that exceeds supply. It is worth mentioning that the costs for obtaining organs are considered high. However, few studies have been developed on analyzing the costs of obtaining organs and tissues for transplants in order to support the decision-making of managers and health professionals.

OBJECTIVE

To summarize the studies related to the cost of obtaining organs for transplants from a deceased donor.

METHOD

A systematic literature review was conducted in the following databases: PubMed, Cochrane Library CINAHAL, Virtual Health Library (BVS), SCOPUS, Web of Science and EMBASE, using the following descriptors: Costs and cost analysis; Donor Selection; Tissue and Organ Procurement; Tissue and Organ Harvesting; and Tissue Donors, in studies published until April 2021. The risk of bias assessment was performed using the Joanna Briggs Institute's Checklist for Economic Assessments. It was not possible to perform a meta-analysis due to the heterogeneity of the studies.

RESULTS

A total of 1731 studies were identified, of which 11 were analyzed. The cost of kidneys in US dollars (USD) ranged between USD $1672 and USD $25,058. Obtaining a liver ranged from USD $586 to USD $44,478. Heart procurement ranged from USD $633 to USD $24,264. The combined heart-lung transplant ranged from USD $860 to USD $23,203. Obtaining the pancreas ranged from USD $413 to USD $29,708.

CONCLUSIONS

Cost of obtaining organs for transplants from a deceased donor is substantial and varies widely across different studies. The overall cost of failures to obtain organs is currently unknown. Understanding organ procurement expenses can help clarify areas in which organ and tissue procurement can improve in cost and efficiency.

摘要

简介

尽管供体器官的需求量超过了供应量,但全球范围内的器官移植数量仍在不断增加。值得注意的是,获取器官的成本被认为是很高的。然而,很少有研究致力于分析获取器官和组织用于移植的成本,以支持管理者和卫生专业人员的决策。

目的

总结与获取已故供体器官移植相关成本的研究。

方法

在以下数据库中进行了系统的文献回顾:PubMed、Cochrane Library CINAHAL、Virtual Health Library(BVS)、SCOPUS、Web of Science 和 EMBASE,使用了以下描述符:成本和成本分析;供体选择;组织和器官获取;组织和器官收获;和组织供体,研究截止到 2021 年 4 月发表。使用 Joanna Briggs 研究所经济评估清单评估偏倚风险。由于研究的异质性,无法进行荟萃分析。

结果

共确定了 1731 项研究,其中分析了 11 项研究。以美元(USD)计价的肾脏成本范围在 1672 美元至 25058 美元之间。获取肝脏的成本在 586 美元至 44478 美元之间。心脏采购的价格在 633 美元至 24264 美元之间。联合心脏-肺移植的价格在 860 美元至 23203 美元之间。获取胰腺的价格在 413 美元至 29708 美元之间。

结论

从已故供体获取器官用于移植的成本相当大,并且在不同的研究中差异很大。目前尚不清楚未能获取器官的总费用。了解器官采购费用可以帮助澄清在哪些方面可以提高器官和组织采购的成本效益。

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