Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology/Diyarbakır/Turkey.
Dicle University, Faculty of Medicine, Department of Pathology/Diyarbakır/Turkey.
Afr Health Sci. 2022 Mar;22(1):125-132. doi: 10.4314/ahs.v22i1.16.
Although endometrial polyps are generally benign, there are also risks of malignancy.
To determine the premalignancy and malignancy prevalence in patients diagnosed with endometrial polyps and to investigate factors affecting premalignancy and malignancy.
In our retrospective study, patients who were diagnosed with endometrial polyp with endometrial samples and who underwent polypectomy by hysteroscopy or hysterectomy within one year were included.
Premalignant / malignant histopathological results were detected in 7 (2.8%) patients. There were no statistically significant differences in histopathological results and endometrial sampling indications between premenopausal and postmenopausal patients. Hysterectomy in patients with premalignant/ malignant results and hysteroscopy in patients with benign results were found to be significantly different. There was not a statistically significant difference between patients with benign results and those with premalignant/malignant results in menopausal status, symptoms, status of hormone replacement therapy and endometrial polyp size.
The possibility of premalignant/ malignant results in patients diagnosed with endometrial polyps should be kept in mind. The menopausal status, symptoms, sizes of endometrial polyps and whether or not the patient is on hormone replacement therapy should be considered while making the management plan. However, these should not be the decisive factors on their own.
尽管子宫内膜息肉通常是良性的,但也存在恶性肿瘤的风险。
确定诊断为子宫内膜息肉的患者的癌前病变和恶性肿瘤患病率,并研究影响癌前病变和恶性肿瘤的因素。
在我们的回顾性研究中,纳入了在一年内通过宫腔镜或子宫切除术进行子宫内膜息肉切除术且有子宫内膜样本的患者。
7 名(2.8%)患者的组织病理学结果显示为癌前/恶性。绝经前和绝经后患者的组织病理学结果和子宫内膜取样指征无统计学差异。在有癌前/恶性结果的患者中进行子宫切除术和在良性结果的患者中进行宫腔镜检查有显著差异。在良性结果和癌前/恶性结果的患者之间,绝经状态、症状、激素替代治疗状态和子宫内膜息肉大小无统计学差异。
对于诊断为子宫内膜息肉的患者,应注意其有癌前/恶性结果的可能性。在制定治疗计划时,应考虑患者的绝经状态、症状、子宫内膜息肉大小以及是否正在接受激素替代治疗。但是,这些因素本身不应成为决定性因素。