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埃塞俄比亚西南部本齐马吉地区育龄妇女乙型肝炎病毒表面抗原血清流行率及相关因素:基于社区的横断面研究。

Sero-prevalence of Hepatitis B virus surface antigen and associated factors among women of reproductive age in Bench Maji Zone, Southwest Ethiopia: Community based cross-sectional study.

机构信息

Mizan Tepi University, College of Health Sciences, Department of Nursing, MizanTeferi, P.O. Box 260, Bench Maji Zone, SNNPR, Ethiopia.

出版信息

Afr Health Sci. 2022 Mar;22(1):496-503. doi: 10.4314/ahs.v22i1.58.

Abstract

BACKGROUND

Hepatitis B virus infection is one of the leading causes of liver diseases which occurs worldwide particularly in developing countries. It is often caused by prenatal transmission from mother to child or household transmission from a close contact during early childhood. It causes different complications like; jaundice, induces premature labor, and prematurity.

OBJECTIVE

The aim of this study was to estimate the sero-prevalence of hepatitis B virus surface antigen and associated factors among women of reproductive age in Bench Maji Zone, South West Ethiopia.

METHODS

A community-based cross-sectional study was conducted from December 15th, 2016 to February 15th, 2017. Multistage sampling technique was applied to select study participants. Logistic regression analysis was applied and p-values < 0.05 was used to see the significant association between dependent and independent variables.

RESULTS

A total of 330 participants were included in this study yielding 98.8% response rate. The sero-prevalence of hbsag among women of reproductive age was 28(8.5%). Having multiple sexual partners (AOR = 18.73, 95% CI = [3.65, 96.21) history of unprotected sex (AOR = 9.39, 95% CI = [1.64, 53.77) were found to be significantly associated with sero-prevalence of HBV.

CONCLUSIONS

The sero-prevalence of HBV infection among women of reproductive age was highly endemic. Hence, behavioral education and communication programs focusing on reduction of risky sexual behaviors should be designed to reduce HBV infection.

摘要

背景

乙型肝炎病毒感染是全球范围内导致肝脏疾病的主要原因之一,尤其在发展中国家更为常见。它通常是由母婴垂直传播或儿童早期与密切接触者的家庭内传播引起的。它会导致不同的并发症,如黄疸、早产和不成熟。

目的

本研究旨在估计班奇马吉地区育龄妇女乙型肝炎病毒表面抗原的血清流行率及其相关因素。

方法

本研究为 2016 年 12 月 15 日至 2017 年 2 月 15 日进行的一项基于社区的横断面研究。采用多阶段抽样技术选择研究参与者。应用逻辑回归分析,p 值<0.05 用于观察因变量与自变量之间的显著关联。

结果

本研究共纳入 330 名参与者,应答率为 98.8%。育龄妇女乙型肝炎表面抗原的血清流行率为 28(8.5%)。有多个性伴侣(AOR=18.73,95%CI=[3.65,96.21])和无保护性行为史(AOR=9.39,95%CI=[1.64,53.77])与乙型肝炎病毒的血清流行率显著相关。

结论

育龄妇女乙型肝炎病毒感染的血清流行率高度流行。因此,应设计针对减少危险性行为的行为教育和沟通计划,以降低乙型肝炎病毒感染的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f57b/9382473/bd096f7afe24/AFHS2201-0496Fig1.jpg

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