Department of Physiotherapy, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, South Africa.
Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa1; and.
Afr Health Sci. 2022 Mar;22(1):312-321. doi: 10.4314/ahs.v22i1.38.
Lifestyle-related factors have been linked with risk for colorectal cancer. Data describing the relationship between lifestyle factors of South African patients who present with colorectal cancer and their survival is sparse.
The objectives were to describe the profile of patients with colorectal cancer; to determine the association between lifestyle-related factors and survival, and to compare results of patients in the private and public sectors.
A retrospective review and secondary analysis of information of patients with colorectal cancer were conducted. The independent samples t-test and Mann Whitney U test were administered to determine differences in the clinical presentation. Pearson's Chi-Squared and Eta (η) tests were used to determine the association between survival and lifestyle-related factors.
Data of 441 patients were included. When compared to the public sector cohort, patients in the private sector cohort were older (p=0.0110), had earlier stages of cancer at the time of diagnosis (p<0.001), had a higher percentage of current alcohol consumption (p<0.001) and had higher survival rates (p<0.001). Waist circumference was shown to have a large-strength effect on survival (η2=0.266).
Emphasis should be placed on anthropometric screening and education to effect long-term behaviour change. Physiotherapists are well placed to provide screening and non-pharmacological interventions for patients with colorectal cancer.
生活方式相关因素与结直肠癌风险相关。描述南非结直肠癌患者生活方式因素与其生存之间关系的数据很少。
描述结直肠癌患者的特征；确定与生活方式相关因素与生存之间的关联，并比较私营和公共部门患者的结果。
对结直肠癌患者的信息进行回顾性审查和二次分析。采用独立样本 t 检验和曼惠特尼 U 检验来确定临床表现的差异。采用皮尔逊卡方检验和 eta（η）检验来确定生存与生活方式相关因素之间的关联。
共纳入 441 例患者的数据。与公共部门队列相比，私营部门队列的患者年龄更大（p=0.0110），诊断时癌症分期更早（p<0.001），当前饮酒的比例更高（p<0.001），生存率更高（p<0.001）。腰围与生存有较大的强度效应（η2=0.266）。
应重视人体测量筛查和教育，以实现长期行为改变。物理治疗师为结直肠癌患者提供筛查和非药物干预的最佳选择。
