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希腊西北部住院及自我隔离的新冠病毒感染患者的临床症状——与嗅觉和味觉功能障碍的关联

Clinical Symptoms in Hospitalized and Self-Quarantined Patients with SARS-CoV-2 Infection in Northwestern Greece - Association with Olfactory and Gustatory Dysfunction.

作者信息

Zarachi Athina, Pezoulas Vasileios, Komnos Ioannis, Lianou Aikaterini, Milionis Orestis, Klouras Eleutherios, Katsikatsos Konstantinos, Fotiadis Dimitrios, Kastanioudakis Ioannis, Milionis Charalampos, Liontos Angelos

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Ioannina, Greece.

出版信息

Maedica (Bucur). 2022 Jun;17(2):277-284. doi: 10.26574/maedica.2022.17.2.277.

Abstract

We aimed to assess the relation of chemosensory dysfunction with the reported symptoms in two subgroups of patients in Northwestern Greece: the first one included patients with moderate to severe symptomatology who needed hospitalization and the second one, patients with mild symptoms who recovered at home. We used a questionnaire to select information about patient demographics, medical history and reported symptoms during infection. Three hundred COVID-19 positive patients who were identified via RT-PCR test in the University Hospital of Ioannina, Greece, were included in the present study, of which 150 recovered at home and the remaining 150 needed hospitalization. Statistical analysis was based on IBM-SPSS Statistics 26.0. The majority of patients had fever during infection, while o minor percentage of those who needed hospitalization (12.67%) suffered from sore throat. There was a statistically significant difference between the loss of smell and clinical symptoms including fatigue, nose congestion, body aches and headache, and loss of taste and reported symptoms including fatigue, body aches, runny nose, headache and sore throat. Fever was the symptom with the highest percentage rate, while sore throat was the symptom with the lowest percentage rate. There are reported clinical symptoms related with olfactory and gustatory dysfunction during COVID-19 infection.

摘要

我们旨在评估希腊西北部两个亚组患者的化学感觉功能障碍与报告症状之间的关系

第一组包括有中度至重度症状且需要住院治疗的患者,第二组是症状较轻且在家中康复的患者。我们使用一份问卷来收集有关患者人口统计学、病史以及感染期间报告症状的信息。本研究纳入了希腊约阿尼纳大学医院通过逆转录聚合酶链反应(RT-PCR)检测确诊的300例新冠肺炎阳性患者,其中150例在家中康复,其余150例需要住院治疗。统计分析基于IBM-SPSS Statistics 26.0。大多数患者在感染期间出现发热,而需要住院治疗的患者中少数(12.67%)有喉咙痛症状。嗅觉丧失与包括疲劳、鼻塞、身体疼痛和头痛在内的临床症状之间,以及味觉丧失与包括疲劳、身体疼痛、流鼻涕、头痛和喉咙痛在内的报告症状之间,存在统计学上的显著差异。发热是发生率最高的症状,而喉咙痛是发生率最低的症状。据报告,新冠肺炎感染期间存在与嗅觉和味觉功能障碍相关的临床症状。

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Role of fever and ambient temperature in COVID-19.发热和环境温度在新冠病毒病中的作用。
Expert Rev Respir Med. 2021 Feb;15(2):171-173. doi: 10.1080/17476348.2020.1816172. Epub 2020 Sep 9.

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