Simson I W
S Afr Med J. 1987 Jul 4;72(1):11-4.
The causes of chronic hepatic venous outflow obstruction are membranous obstruction of the inferior vena cava (group 1), hepatic venous ostial obstruction (group 2) and partial hepatic venous ostial obstruction (group 3). At the H. F. Verwoerd and Kalafong Hospitals, Pretoria, 155 cases have been diagnosed, almost all in the first group. Over 50% of the patients in this series had hepatocellular carcinoma; this association appears to be a constant finding world-wide. The most likely cause is a chronic hepatocaval thrombosis with organisation, leading to fibrous stenosis or membranous occlusion of the involved veins.
慢性肝静脉流出道梗阻的病因包括下腔静脉膜性梗阻（第1组）、肝静脉开口处梗阻（第2组）和部分肝静脉开口处梗阻（第3组）。在比勒陀利亚的H.F.韦尔沃德医院和卡拉方医院，已诊断出155例病例，几乎全部属于第1组。该系列中超过50%的患者患有肝细胞癌；这种关联似乎在全球范围内都是一个常见的发现。最可能的原因是慢性肝腔静脉血栓形成并机化，导致受累静脉出现纤维性狭窄或膜性闭塞。
