Alene Tilahun Dessie, Abebe Melese Shenkut
Department of Pediatrics, School of Medicine, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
Department of Anatomy, School of Medicine, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
Int Med Case Rep J. 2022 Aug 22;15:425-429. doi: 10.2147/IMCRJ.S381186. eCollection 2022.
The development of conjoined twins always catches the eyes of researchers and clinicians. Beyond the rareness of the cases, how they develop is a debatable issue. This report presented a case of ischiopagus conjoined twins who had two heads (dicephalus), four upper extremities (tetrabrachius), and were joined below the chest with two lower extremities (bipus). The twin's mother was referred from a primary hospital to Dessie Comprehensive Specialized Hospital for proper management of twin pregnancy, where a cesarean section was performed. The mother and her husband have no family history of birth defects or exposure to known teratogens. On imaging, the twins had separate hearts, lungs, and kidneys but a single liver, spleen, stomach, and intestine. They also shared genitourinary structures: a single penis with sub-coronal hypospadias and one imperforate anus. In addition, their placenta was single with one umbilical vein and two umbilical arteries. The conjoined twins had multiple accompanying cardiovascular anomalies but no external craniofacial, extremity, or brain anomalies. They passed away after 36 hours of follow-up in the neonatal intensive care unit at Dessie Comprehensive Specialized Hospital.
联体双胎的发育一直吸引着研究人员和临床医生的关注。除了病例的罕见性之外，它们的发育过程也是一个有争议的问题。本报告介绍了一例坐骨联体双胎病例，该双胎有两个头（双头畸形）、四条上肢（四臂畸形），胸部以下相连，有两条下肢（双足畸形）。双胞胎的母亲从一家基层医院转诊至德西综合专科医院，以便对双胎妊娠进行妥善管理，并在该院进行了剖宫产。母亲和她的丈夫没有出生缺陷家族史，也没有接触过已知的致畸物。影像学检查显示，双胞胎有各自独立的心脏、肺和肾脏，但共用一个肝脏、脾脏、胃和肠道。他们还共享泌尿生殖结构：一个阴茎伴有冠状沟下尿道下裂和一个肛门闭锁。此外，他们的胎盘是单一的，有一条脐静脉和两条脐动脉。联体双胎伴有多种心血管异常，但无外部颅面、肢体或脑部异常。在德西综合专科医院新生儿重症监护病房进行36小时的随访后，他们去世了。
