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甲状腺乳头状微小癌伴对侧肱骨大转移及颈部淋巴结转移:一例报告

Papillary thyroid microcarcinoma with contralateral large humerus metastasis and cervical lymph node metastasis: A case report.

作者信息

Gong Yi, Tang Shixiong, Tan Wanlin, Liao Liyan, Li Xiaodu, Niu Chengcheng

机构信息

Department of Thyroid Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.

Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.

出版信息

Front Oncol. 2022 Aug 10;12:924465. doi: 10.3389/fonc.2022.924465. eCollection 2022.

Abstract

INTRODUCTION

Papillary thyroid microcarcinoma (PTMC) that metastasizes to bone, especially metastasizes to contralateral humerus with so large mass, is rarely reported before.

CASE REPORT

We presented a 50-year-old female patient with a large painful mass in the right humerus for 5 years, presenting with swelling of the right shoulder with limited mobility. Positron emission tomography-computed tomography (PET/CT) showed a large mass in the right humerus, bilateral lung lesions, and enlarged lymph nodes in the right supraclavicular fossa. Right humerus lesion biopsy and immunohistochemical evaluations confirmed that the lesion originated from the thyroid tissue. Then, the thyroid ultrasonography showed a hypo-echoic solid nodule with an irregular taller-than-wide shape in the upper of left thyroid lobe and enlarged lymph nodes with the absence of fatty hilum in the contralateral right IV compartment. The total thyroidectomy and cervical lymph node dissection were undertaken; the histopathology confirmed the diagnosis of PTMC with contralateral cervical lymph node metastasis.

CONCLUSION

We reported a case of PTMC with contralateral large humerus and cervical lymph node metastasis and demonstrated the PET/CT images of the metastatic large humerus and thyroid ultrasonographic appearances of the PTMC and enlarged cervical lymph node.

摘要

引言

甲状腺微小乳头状癌(PTMC)转移至骨,尤其是转移至对侧肱骨且肿块如此之大的情况,此前鲜有报道。

病例报告

我们报告了一名50岁女性患者,其右侧肱骨出现疼痛性大肿块5年,表现为右肩部肿胀,活动受限。正电子发射断层扫描-计算机断层扫描(PET/CT)显示右侧肱骨有一个大肿块、双侧肺部病变以及右锁骨上窝淋巴结肿大。右侧肱骨病变活检及免疫组化评估证实该病变起源于甲状腺组织。随后,甲状腺超声检查显示左叶甲状腺上部有一个低回声实性结节,呈不规则的高大于宽形态,以及对侧右侧IV区淋巴结肿大且无脂肪门。进行了全甲状腺切除术及颈部淋巴结清扫;组织病理学证实为PTMC伴对侧颈部淋巴结转移。

结论

我们报告了一例PTMC伴对侧肱骨及颈部淋巴结转移的病例,并展示了转移性大肱骨的PET/CT图像以及PTMC和肿大颈部淋巴结的甲状腺超声表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/511e/9400018/6588aed58291/fonc-12-924465-g001.jpg

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