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[支气管哮喘患者运动时呼吸和循环系统的功能变化]

[Functional shifts in the respiratory and circulatory systems of bronchial asthma patients during exertion].

作者信息

Abdusalamov A B, Mil'man M Sh, Faĭnberg I F

出版信息

Ter Arkh. 1987;59(3):45-7.

PMID:3603389
Abstract

A total of 56 patients aged 40-59 were examined for bronchial asthma of infectious-allergic etiology and moderate severity. Exercise-related bronchospasm (EB) was detected in 46 of them. Exercise tolerance was studied using bicycle ergometry, ventilometric changes with threshold exercise test and central hemodynamics was assessed in response to standard exercise with chest tetrapolar rheography. BE was associated with an additional decrease in the working capacity of patients with bronchial asthma with moderately expressed ventilation disturbances at rest. These patients were also demonstrated to have hypoergic-nature response of central hemodynamics to a standard motor test. BE-free patients with the same degree of ventilation disturbances exhibited the response close to normoergic. The evidence suggests the involvement of the hemodynamic mechanisms in the formation of an exercise tolerance threshold in bronchial asthma complicated by BE.

摘要

对56名年龄在40至59岁之间、患有感染性 - 过敏性病因且病情为中度严重的支气管哮喘患者进行了检查。其中46人检测出运动诱发性支气管痉挛(EB)。使用自行车测力计研究运动耐力,通过阈值运动试验评估通气量变化,并采用胸部四极血流图对标准运动时的中心血流动力学进行评估。EB与支气管哮喘患者在休息时通气障碍表现为中度时工作能力的额外下降有关。这些患者还表现出中心血流动力学对标准运动试验的低反应性。具有相同程度通气障碍但无EB的患者表现出接近正常反应性的反应。证据表明血流动力学机制参与了合并EB的支气管哮喘运动耐力阈值的形成。

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