Princi Pietro, Gallo Gaetano, Tempera Serena Elisa, Umbriano Antonio, Goglia Marta, Andreoli Federica, Nigro Casimiro
UOC Centro Multifunzionale di Chirurgia Endocrina, Ospedale Cristo Re, Roma, Italy.
Department of Surgical Sciences, Sapienza University of Roma, Roma, Italy.
Front Surg. 2022 Aug 10;9:983966. doi: 10.3389/fsurg.2022.983966. eCollection 2022.
The most fearsome complication in thyroid surgery is the temporary or definitive recurrent laryngeal nerve (RLN) injury. The aim of our study was to evaluate the impact of intraoperative neuromonitoring (IONM) on postoperative outcomes after thyroid and parathyroid surgery. From October 2014 to February 2016, a total of 80 consecutive patients, with high risk of RLN injuries, underwent thyroid and parathyroid surgery. They were divided in two groups (IONM group and control group), depending on whether neuromonitoring was used or not. We used the Nerve Integrity Monitoring System (NIM)-Response 3.0® (Medtronic Xomed®). The operation time ( = 0.014). and the length of hospital stay (LOS) ( = 0.14) were shorter in the IONM group. Overall mean follow-up was 96.7 ± 14.3 months. The rate of transient RLN palsy was 2.6% in IONM group and 2.5% in the control group ( = not significant). Only one case of definitive RLN injury was reported in control group. No differences were reported between the two groups in terms of temporary or definitive RLN injury. Routine use of IOMN increases the surgery cost, but overall, it leads to long-term cost savings thanks to the reduction of both operating times (106.3 ± 38.7 vs 128.1 ± 39.3, p: 0.01) and LOS (3.2 ± 1.5 vs 3.7 ± 1.5 days, = 0.14). Anatomical visualization of RLN remains the gold standard in thyroid and parathyroid surgery. Nevertheless, IONM is proved to be a valid help without the ambition to replace surgeon's experience.
甲状腺手术中最可怕的并发症是暂时性或永久性喉返神经(RLN)损伤。我们研究的目的是评估术中神经监测(IONM)对甲状腺和甲状旁腺手术后的术后结果的影响。2014年10月至2016年2月,共有80例连续的具有喉返神经损伤高风险的患者接受了甲状腺和甲状旁腺手术。根据是否使用神经监测,将他们分为两组(IONM组和对照组)。我们使用了神经完整性监测系统(NIM)-Response 3.0®(美敦力索迈德®)。IONM组的手术时间(=0.014)和住院时间(LOS)(=0.14)较短。总体平均随访时间为96.7±14.3个月。IONM组的暂时性喉返神经麻痹发生率为2.6%,对照组为2.5%(=无显著性差异)。对照组仅报告了1例永久性喉返神经损伤。两组在暂时性或永久性喉返神经损伤方面没有差异。常规使用IONM会增加手术成本,但总体而言,由于手术时间(106.3±38.7对128.1±39.3,p:0.01)和住院时间(3.2±1.5对3.7±1.5天,=0.14)的减少,它会带来长期成本节约。喉返神经的解剖可视化仍然是甲状腺和甲状旁腺手术的金标准。然而,IONM被证明是一种有效的辅助手段,无意取代外科医生的经验。