Saracco Michela, Fulchignoni Camillo, Fusco Fabrizio, Logroscino Giandomenico
Department of Orthopaedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma - Università Cattolica del Sacro Cuore, Rome, Italy.
Department of Orthopaedics and Trauma, Osp. "San Giovanni di Dio" - ASL Napoli 2 Nord, Napoli, Italy.
Orthop Rev (Pavia). 2022 Aug 25;14(3):37575. doi: 10.52965/001c.37575. eCollection 2022.
Humeral diaphyseal fractures are very common. Many treatments have been proposed but the choice of the best one is often complex.
The aim of the proposed study is to analyze the data in the literature in order to define the risks, advantages and disadvantages of the alternative surgical treatments (anterograde/retrograde intramedullary nailing, ORIF, MIPO).
PubMed / Medline and Google Scholar were searched for prospective randomized or case-control retrospective studies about surgical treatment of humeral diaphyseal fractures with nailing, ORIF and MIPO, according to PRISMA guidelines. The primary outcome considered was the fracture healing time by comparing nailing-ORIF, nailing-MIPO and ORIF-MIPO. Differences in the rate of post-operative complications, patient satisfaction, intra-operative blood loss and surgical time were considered secondary outcomes.
506 studies were identified, but only 10 studies were valid for the systematic review. No differences between nailing, ORIF and MIPO were recorded in terms of healing and surgical times. Intra-operative blood loss was significantly higher during ORIF (p 0.024). No differences were found in the restoration of function evaluated using clinical scales. The rate of complications was 27.4% for nailing, 21.2% for ORIF and 13.8% for MIPO. The difference was statistically significant only by comparing nailing with MIPO (p 0.012), probably because anterograde nailing is more often correlated to shoulder impairment. ORIF was at higher risk of infection compared to nailing (p 0.007).
Humeral diaphyseal fractures require careful pre-operative planning, ensuring reduced healing time, less soft tissue damage and low rate of complications. The lower exposure of the fracture allows for excellent results with reduced bleeding and lower risk of complications.
肱骨干骨折非常常见。虽然已经提出了许多治疗方法,但选择最佳治疗方法往往很复杂。
本研究的目的是分析文献中的数据,以确定替代性手术治疗方法(顺行/逆行髓内钉固定、切开复位内固定术、微创钢板接骨术)的风险、优点和缺点。
根据PRISMA指南,在PubMed/Medline和谷歌学术上搜索关于使用髓内钉固定、切开复位内固定术和微创钢板接骨术治疗肱骨干骨折的前瞻性随机或病例对照回顾性研究。主要观察指标是通过比较髓内钉固定与切开复位内固定术、髓内钉固定与微创钢板接骨术以及切开复位内固定术与微创钢板接骨术来评估骨折愈合时间。术后并发症发生率、患者满意度、术中失血量和手术时间的差异被视为次要观察指标。
共识别出506项研究,但只有10项研究可用于系统评价。在愈合时间和手术时间方面,髓内钉固定、切开复位内固定术和微创钢板接骨术之间没有差异。切开复位内固定术期间的术中失血量显著更高(p = 0.024)。使用临床量表评估功能恢复情况时未发现差异。髓内钉固定的并发症发生率为27.4%,切开复位内固定术为21.2%,微创钢板接骨术为13.8%。仅在比较髓内钉固定与微创钢板接骨术时,差异具有统计学意义(p = 0.012),这可能是因为顺行髓内钉固定更常与肩部损伤相关。与髓内钉固定相比,切开复位内固定术感染风险更高(p = 0.007)。
肱骨干骨折需要仔细的术前规划,以确保缩短愈合时间、减少软组织损伤并降低并发症发生率。骨折暴露程度较低可实现良好的治疗效果,同时减少出血和并发症风险。