Crosier Rebecca, McPherson Ruth
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada.
CJC Open. 2022 Jun 9;4(8):732-734. doi: 10.1016/j.cjco.2022.05.001. eCollection 2022 Aug.
The ketogenic diet (KD) is currently popular for the achievement of weight loss and improvement in glycemic variables. The diet allows consumption of foods high in fat and protein, with strict limitation of carbohydrates. We present a case series of substantial increases in total cholesterol and low-density lipoprotein cholesterol following the initiation of a KD, with improvements in cholesterol levels once the KD was stopped. Novel teaching points include the need for lipid monitoring in patients who choose to follow a KD and for raising awareness of the extreme lipid response that can occur in some patients, particularly lean individuals.
生酮饮食（KD）目前因有助于减肥和改善血糖指标而受到欢迎。该饮食允许食用高脂肪和高蛋白食物，严格限制碳水化合物的摄入。我们报告了一系列病例，这些病例显示在开始生酮饮食后总胆固醇和低密度脂蛋白胆固醇大幅升高，而在停止生酮饮食后胆固醇水平有所改善。新的要点包括，对于选择采用生酮饮食的患者需要进行血脂监测，以及提高对某些患者（尤其是瘦人）可能出现的极端血脂反应的认识。
