Chen Jianyong, Zhu Haiyue, Shen Jiali, Ma Xiaobao, Wang Wei, Sun Jin, Chen Xiangping, Yang Jun
Department of Otorhinolaryngology-Head & Neck Surgery,Xinhua Hospital,Shanghai Jiaotong University School of Medicine;Shanghai Jiaotong University School of Medicine Ear Institute;Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases,Shanghai,200092,China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Sep;36(9):679-684. doi: 10.13201/j.issn.2096-7993.2022.09.006.
To investigate the correlation between Mandarin acceptable noise level (M-ANL) and cortical auditory evoked potential (CAEP), and to explore the possible mechanism leading to individual differences in M-ANL values. Thirty listeners aged 22-33 years with normal hearing were selected as the study subjects, and the M-ANL test and CAEP test were performed respectively. The most comfortable level (MCL), maximum background noise level (BNL), M-ANL and CAEP values of each subject were recorded. The latency of each wave of P1, N1, P2, N2, P300 and the amplitude of P1-N1, P2-N2, P300 in CAEP were recorded for each subject. SPSS 25.0 was used for statistical analysis to explore the correlation between the MCL value, BNL value and M-ANL values and the latency of P1, N1, P2, N2, P300 and P1-N1, P2-N2, P300 amplitudes of CAEP. ①The MCL value and M-ANL value were positively correlated with the P2 latency of CAEP, and the correlation coefficients were 0.404 and 0.400, respectively, and the differences were statistically significant (<0.05). There was no correlation with P1, N1, N2, and P300 latencies of CAEP (>0.05). ②The MCL value, BNL value and M-ANL value had no significant difference with the CAEP wave amplitudes of P1-N1, P2-N2, and P300 (>0.05). There was a certain correlation between M-ANL and CAEP in young adults with normal hearing, suggesting that the central auditory cortex might play a potential regulatory role in the background noise tolerance. Individuals with a greater background noise acceptance might have stronger central efferent mechanisms and/or less active central afferent mechanisms.
为探讨普通话可接受噪声级(M-ANL)与皮质听觉诱发电位(CAEP)之间的相关性,并探究导致M-ANL值个体差异的可能机制。选取30名年龄在22 - 33岁、听力正常的受试者作为研究对象,分别进行M-ANL测试和CAEP测试。记录每位受试者的最舒适响度级(MCL)、最大背景噪声级(BNL)、M-ANL及CAEP值。记录每位受试者CAEP中P1、N1、P2、N2、P300各波的潜伏期以及P1-N1、P2-N2、P300的波幅。采用SPSS 25.0进行统计分析,以探究MCL值、BNL值和M-ANL值与CAEP中P1、N1、P2、N2、P300潜伏期以及P1-N1、P2-N2、P300波幅之间的相关性。①MCL值和M-ANL值与CAEP的P2潜伏期呈正相关,相关系数分别为0.404和0.400,差异有统计学意义(<0.05)。与CAEP的P1、N1、N2和P300潜伏期无相关性(>0.05)。②MCL值、BNL值和M-ANL值与CAEP的P1-N1、P2-N2和P300波幅无显著差异(>0.05)。听力正常的年轻成年人中M-ANL与CAEP之间存在一定相关性,提示中枢听觉皮层可能在背景噪声耐受性方面发挥潜在调节作用。背景噪声接受度较高的个体可能具有更强的中枢传出机制和/或更不活跃的中枢传入机制。