Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen, Vietnam.
School of Public Health, Curtin University, Perth, WA, Australia.
Qual Life Res. 2023 Jan;32(1):71-79. doi: 10.1007/s11136-022-03237-5. Epub 2022 Aug 29.
Data regarding the health-related quality of life (HRQoL) in men and women after percutaneous coronary intervention (PCI) in low-and-middle incomes countries remains scarce. To investigate sex difference in the HRQoL at 30 days and 12 months post PCI in Vietnam.
We used data from a single percutaneous coronary registry established in the Vietnam National Heart Institute. The HRQoL was measured using the EQ-5D-3L instrument via telephone interviews, and information about demographics, clinical presentation and procedures was obtained through face-to-face interviews and medical records. The HRQoL between men and women were compared using independent samples t tests, the Mann-Whitney U test or univariate/multivariate logistic regression.
There were 866 patients included in this cohort, with the proportion of women being nearly half of men (32.1 vs 67.9%). Women were 3.5 years older, had lower income and educational levels but greater prevalence of cardiovascular risk factors. At 30 days, women significantly had more problems in mobility, personal care and pain/discomfort compared to men. At 12 months, women had more problem than men in usual activity. The geometric means of HRQoL was lower in women at 30 days, but not in 12 months. From 30 days to 12 months after discharge, women showed better recovery in mobility compared to men, but not in other dimensions.
In this first insight of sex differences in HRQoL following PCI in Vietnam, women appeared to have worse quality of life, especially at 30 days after discharge but they showed better recovery in mobility at 12 months compared to men.
在中低收入国家，经皮冠状动脉介入治疗（PCI）后男性和女性健康相关生活质量（HRQoL）的数据仍然很少。本研究旨在调查越南 PCI 后 30 天和 12 个月时 HRQoL 的性别差异。
我们使用了在越南国家心脏研究所建立的单一经皮冠状动脉注册研究的数据。通过电话访谈使用 EQ-5D-3L 工具测量 HRQoL，并通过面对面访谈和病历获得人口统计学、临床表现和手术程序信息。使用独立样本 t 检验、Mann-Whitney U 检验或单变量/多变量逻辑回归比较男性和女性之间的 HRQoL。
该队列共纳入 866 例患者，女性比例接近男性的一半（32.1% vs. 67.9%）。女性比男性年长 3.5 岁，收入和教育水平较低，但心血管危险因素的患病率较高。在 30 天时，与男性相比，女性在移动、个人护理和疼痛/不适方面的问题明显更多。在 12 个月时，女性在日常活动方面的问题比男性多。女性在 30 天时的 HRQoL 几何平均值较低，但在 12 个月时则不然。从出院后 30 天到 12 个月，与男性相比，女性在移动方面的恢复情况更好，但在其他方面则不然。
在越南 PCI 后 HRQoL 性别差异的首次研究中，女性的生活质量似乎较差，尤其是在出院后 30 天，但与男性相比，女性在 12 个月时在移动方面的恢复情况更好。
