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在疾病的第一个高峰期转诊至医院的新冠病毒肺炎患者:常见临床症状包括肌痛和疲劳。

COVID-19 patients at referral to hospital during the first peak of disease: Common clinical findings including myalgia and fatigue.

作者信息

Honarmand Amin, Sheybani Fateme, Aflatoonian Elahe, Saberinia Amin

机构信息

Department of Emergency Medicine, School of Medicine, Kerman University of Medical Sciences, Kerman.

Kerman University of Medical Sciences, Kerman.

出版信息

Eur J Transl Myol. 2022 Aug 12;32(3):10731. doi: 10.4081/ejtm.2022.10731.

DOI:10.4081/ejtm.2022.10731
PMID:36036352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9580529/
Abstract

The wide range of manifestations and clinical symptoms of COVID-19 has made it a unique disease. Investigating the epidemiology of different clinical manifestations of this disease in patients referred to medical centers is one of the most effective steps in adopting a suitable diagnostic and treatment approach. These findings also provide a basis for comparing the evolution of the virus and its clinical manifestations over time and at different peaks of the disease. Therefore, the present study was aimed at investigating common clinical findings at the time of referral in patients with COVID-19 in Afzalipour Hospital, Kerman, during the first peak of the disease. This descriptive-analytical cross-sectional study was performed on hospitalized patients diagnosed with COVID-19, between March 2020 and June 2020. The patients were included in the study by census method, and the research variables related to demographic indicators, disease course and clinical symptoms were extracted from the patients' medical records, and then subjected to statistical analysis. In this study, a total of 210 patients were examined, consisted mainly of male patients (59.5%). The mean age was found to be 53.95 ± 19.55 years. Also, 20.3% of patients needed admission in the intensive care unit. In addition, 1% of patients were infected in February 2020, 24% in March 2020, 47.4% in April 2020 and 27.4% in May 2020. The mean onset of symptoms until hospitalization was also found as 6.51 days. The most common clinical symptoms included shortness of breath (75.7%), dry cough (52.9%), fever (50.5%), myalgia (45.7%) and fatigue (41.9%). Fever at admission time was significantly more common in ages less than 50 years (p=0.034). Our study showed that the most common clinical symptoms were shortness of breath, dry cough, fever, myalgia and fatigue. No statistically significant difference was found in common symptoms between men and women. Among the common clinical symptoms, only fever at admission time was observed to be significantly higher in those under 50 years of age.

摘要

新型冠状病毒肺炎(COVID-19)广泛的临床表现和临床症状使其成为一种独特的疾病。在转诊至医疗中心的患者中调查该疾病不同临床表现的流行病学情况,是采取合适诊断和治疗方法的最有效步骤之一。这些发现也为比较病毒随时间推移以及在疾病不同高峰期的演变及其临床表现提供了依据。因此,本研究旨在调查克尔曼省阿夫扎利普尔医院在疾病首个高峰期转诊时COVID-19患者的常见临床发现。这项描述性分析横断面研究于2020年3月至2020年6月期间对确诊为COVID-19的住院患者进行。采用普查法将患者纳入研究,并从患者病历中提取与人口统计学指标、病程和临床症状相关的研究变量,然后进行统计分析。本研究共检查了210例患者,主要为男性患者(59.5%)。平均年龄为53.95±19.55岁。此外,20.3%的患者需要入住重症监护病房。另外,1%的患者在2020年2月感染,24%在2020年3月感染,47.4%在2020年4月感染,27.4%在2020年5月感染。症状出现至住院的平均时间也为6.51天。最常见的临床症状包括呼吸急促(75.7%)、干咳(52.9%)、发热(50.5%)、肌痛(45.7%)和疲劳(41.9%)。入院时发热在年龄小于50岁的患者中明显更为常见(p=0.034)。我们的研究表明,最常见的临床症状是呼吸急促、干咳、发热、肌痛和疲劳。男性和女性在常见症状方面未发现统计学上的显著差异。在常见临床症状中,仅观察到入院时发热在50岁以下人群中明显更高。

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