马来西亚南部预防疟疾的个人防蚊措施加氯胍

Personal antimosquito measures plus proguanil for malaria prophylaxis in southern Malaysia.

作者信息

Henderson A, Rixom J A

出版信息

Trans R Soc Trop Med Hyg. 1986;80(6):981-2. doi: 10.1016/0035-9203(86)90279-8.

Abstract

During the early months of 1985 and 1986, 408 non-immune British soldiers undertook training in the jungles north of Kota Tinggi, in southern Malaysia. In this geographical location, where malaria transmission is now light, a combination of strict personal antimosquito measures plus proguanil 200 mg daily produced effective, safe protection, with only a single case of vivax malaria occurring. Given the limited malaria risk, however, the results of this study should be extrapolated only with caution to other areas of Malaysia.

摘要

1985年初至1986年期间，408名无免疫力的英国士兵在马来西亚南部哥打丁宜以北的丛林中接受训练。在这个目前疟疾传播轻微的地理位置，严格的个人防蚊措施加上每日200毫克氯胍产生了有效、安全的防护效果，仅出现了1例间日疟病例。然而，鉴于疟疾风险有限，本研究结果仅应谨慎外推至马来西亚的其他地区。