Suppr超能文献

UNIFAN:一种用于无监督单细胞聚类和注释的工具。

UNIFAN: A Tool for Unsupervised Single-Cell Clustering and Annotation.

机构信息

Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

Meakins-Christie Laboratories, Department of Medicine, McGill University Health Centre, Montreal, Canada.

出版信息

J Comput Biol. 2022 Nov;29(11):1229-1232. doi: 10.1089/cmb.2022.0251. Epub 2022 Aug 25.

Abstract

UNIFAN is an unsupervised cell type annotation tool for single-cell RNA sequencing data (scRNA-seq). Given single-cell expression data as input, UNIFAN outputs cell clusters as well as annotations for each cluster. The clustering process utilizes information on pathways and biological processes and these are also used to annotate the resulting clusters. In this software article, we focus on how to install UNIFAN and on the main steps involved in using UNIFAN for cell type annotations.

摘要

UNIFAN 是一种用于单细胞 RNA 测序数据(scRNA-seq)的无监督细胞类型注释工具。给定单细胞表达数据作为输入,UNIFAN 输出细胞簇以及每个簇的注释。聚类过程利用了通路和生物过程的信息,这些信息也用于注释生成的簇。在本软件文章中,我们重点介绍如何安装 UNIFAN 以及使用 UNIFAN 进行细胞类型注释的主要步骤。

相似文献

10
Single-Cell RNAseq Clustering.单细胞RNA测序聚类
Methods Mol Biol. 2023;2584:241-250. doi: 10.1007/978-1-0716-2756-3_12.

本文引用的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验