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Community access to rectal artesunate for malaria (CARAMAL): A large-scale observational implementation study in the Democratic Republic of the Congo, Nigeria and Uganda.社区获取青蒿琥酯直肠给药治疗疟疾项目(CARAMAL):在刚果民主共和国、尼日利亚和乌干达开展的一项大规模观察性实施研究。
PLOS Glob Public Health. 2022 Sep 6;2(9):e0000464. doi: 10.1371/journal.pgph.0000464. eCollection 2022.
2
Definitions of Severity in Treatment Seeking Studies of Febrile Illness in Children in Low and Middle Income Countries: A Scoping Review.中低收入国家儿童发热性疾病治疗寻求研究中严重程度定义:范围综述。
Int J Public Health. 2021 Aug 30;66:634000. doi: 10.3389/ijph.2021.634000. eCollection 2021.
3
Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980-2015.非疟疾性发热性疾病:1980-2015 年非洲发表的病因学研究和病例报告的系统评价。
BMC Med. 2020 Sep 21;18(1):279. doi: 10.1186/s12916-020-01744-1.
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Factors influencing mothers' health care seeking behaviour for their children: evidence from 31 countries in sub-Saharan Africa.影响母亲为其子女寻求医疗保健行为的因素:来自撒哈拉以南非洲 31 个国家的证据。
BMC Health Serv Res. 2020 Sep 7;20(1):842. doi: 10.1186/s12913-020-05683-8.
5
Place of death, care-seeking and care pathway progression in the final illnesses of children under five years of age in sub-Saharan Africa: a systematic review.撒哈拉以南非洲 5 岁以下儿童终末期疾病的死亡地点、寻医和照护途径进展:系统评价。
J Glob Health. 2019 Dec;9(2):020422. doi: 10.7189/jogh.09.020422.
6
Household relationships and healthcare seeking behaviour for common childhood illnesses in sub-Saharan Africa: a cross-national mixed effects analysis.撒哈拉以南非洲地区常见儿童疾病的家庭关系与就医行为:一项跨国混合效应分析。
BMC Health Serv Res. 2019 May 14;19(1):308. doi: 10.1186/s12913-019-4142-x.
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Delivering child health interventions through the private sector in low and middle income countries: challenges, opportunities, and potential next steps.通过私营部门在中低收入国家提供儿童健康干预措施:挑战、机遇和潜在的下一步。
BMJ. 2018 Jul 30;362:k2950. doi: 10.1136/bmj.k2950.
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Impact of introduction of rapid diagnostic tests for malaria on antibiotic prescribing: analysis of observational and randomised studies in public and private healthcare settings.疟疾快速诊断检测的引入对抗生素处方的影响:公共和私立医疗机构的观察性研究与随机研究分析
BMJ. 2017 Mar 29;356:j1054. doi: 10.1136/bmj.j1054.
9
Feasibility of Malaria Diagnosis and Management in Burkina Faso, Nigeria, and Uganda: A Community-Based Observational Study.布基纳法索、尼日利亚和乌干达疟疾诊断与管理的可行性:一项基于社区的观察性研究。
Clin Infect Dis. 2016 Dec 15;63(suppl 5):S245-S255. doi: 10.1093/cid/ciw622.
10
Caregivers' treatment-seeking behaviors and practices in Uganda-A systematic review (Part II).乌干达护理人员的求医行为与做法——系统评价(第二部分)
Acta Trop. 2015 Dec;152:269-281. doi: 10.1016/j.actatropica.2015.07.029. Epub 2015 Aug 7.

乌干达北部有和无严重疾病危险体征发热儿童的求医和治疗:三项家庭调查的结果(2018-2020 年)。

Care Seeking and Treatment of Febrile Children with and without Danger Signs of Severe Disease in Northern Uganda: Results from Three Household Surveys (2018-2020).

机构信息

Makerere University School of Public Health, Kampala, Uganda.

Swiss Tropical and Public Health Institute, Allschwil, Switzerland.

出版信息

Am J Trop Med Hyg. 2022 Aug 29;107(4):934-938. doi: 10.4269/ajtmh.21-1132. Print 2022 Oct 12.

DOI:10.4269/ajtmh.21-1132
PMID:36037867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9651542/
Abstract

Identification, stabilization, and prompt referral of children with signs of severe febrile disease (danger signs) in rural communities are crucial for preventing complications and death from severe malaria, pneumonia, and diarrhea. We set out to determine the treatment-seeking practices and treatment patterns for children < 5 years of age with an acute febrile illness, with or without danger signs of severe disease, in a highly malaria-endemic area of northern Uganda. Three household surveys were conducted from November through December each year in 2018, 2019, and 2020. Overall, 30% of the children in the study were reported to have had a WHO-classified danger sign including convulsions, unconsciousness/unusually sleepy, inability to feed or drink, and vomiting everything. Only half of the children in this study sought care from a health provider. However, significantly more children with danger signs of severe disease sought and received treatment and diagnostics from a health provider, compared with those without danger signs (adjusted odds ratio: 1.6, 95% confidence interval: 1.2-2.0; P < 0.01). In the total population studied, care seeking in the public sector was 26% and similar to care seeking in the private sector (24%). Community health workers were used as the first source of care by 12% of the children. Approximately 38% of the children who were reported to have danger signs of severe disease requiring prompt referral and treatment did not seek care from a health provider. Understanding and addressing barriers to accessing healthcare could contribute to better treatment seeking practices.

摘要

在农村社区,识别、稳定并及时转介出现严重发热症状(危险症状)的儿童,对于预防重症疟疾、肺炎和腹泻导致的并发症和死亡至关重要。我们旨在确定在乌干达北部一个高度疟疾流行地区,5 岁以下患有急性发热疾病且伴有或不伴有严重疾病危险症状的儿童的求诊行为和治疗模式。2018 年至 2020 年 11 月至 12 月期间,每年进行三次家庭调查。总体而言,研究中的 30%的儿童报告出现了世界卫生组织(WHO)分类的危险症状,包括抽搐、意识不清/异常嗜睡、无法进食或饮水以及呕吐物中含有所有东西。只有一半的儿童在本研究中寻求医疗服务。然而,与没有危险症状的儿童相比,患有严重疾病危险症状的儿童明显更多地寻求并接受了医疗服务和诊断(调整后的优势比:1.6,95%置信区间:1.2-2.0;P<0.01)。在研究的总人口中,公共部门的求诊率为 26%,与私营部门相似(24%)。社区卫生工作者被 12%的儿童用作首次求医的来源。约 38%的儿童报告出现需要及时转介和治疗的严重疾病危险症状,但未向医疗机构求诊。了解和解决获得医疗保健的障碍可能有助于改善求诊行为。