Department of Health Behavior and Health Education, University of Michigan, Ann Arbor, Michigan; Firearm Injury & Policy Research Program, Harborview Injury Prevention & Research Center, School of Public Health, University of Washington, Seattle, Washington.
Harborview Injury Prevention & Research Center, School of Public Health, University of Washington, Seattle, Washington.
J Emerg Med. 2022 Aug;63(2):178-191. doi: 10.1016/j.jemermed.2022.04.029. Epub 2022 Aug 26.
Patients with injury may be at high risk of long-term opioid use due to the specific features of injury (e.g., injury severity), as well as patient, treatment, and provider characteristics that may influence their injury-related pain management.
Inform prescribing practices and identify high-risk populations through studying chronic prescription opioid use in the trauma population.
Using the Washington State All-Payer Claims Database (WA-APCD) data, we included adults aged 18-65 years with an incident injury from October 1, 2015-December 31, 2017. We compared patient, injury, treatment, and provider characteristics by whether or not the patients had long-term (≥ 90 days continuous prescription opioid use), or no opioid use after injury.
We identified 191,130 patients who met eligibility criteria and were included in our cohort; 5822 met criteria for long-term use. Most had minor injuries, with a median Injury Severity Score = 1, with no difference between groups. Almost all patients with long-term opioid use had filled an opioid prescription in the year prior to their injury (95.3%), vs. 31.3% in the no-use group (p < 0.001). Comorbidities associated with chronic pain, mental health, and substance use conditions were more common in the long-term than the no-use group.
Across this large cohort of multiple, mostly minor, injury types, long-term opioid use was relatively uncommon, but almost all patients with chronic use post injury had preinjury opioid use. Long-term opioid use after injury may be more closely tied to preinjury chronic pain and pain management than acute care pain management.
由于损伤的特定特征(例如损伤严重程度)以及可能影响其损伤相关疼痛管理的患者、治疗和提供者特征,受伤患者可能长期使用阿片类药物的风险较高。
通过研究创伤人群中慢性处方类阿片类药物的使用情况,为规范处方实践并确定高风险人群提供信息。
我们使用华盛顿州全支付者索赔数据库(WA-APCD)数据,纳入了 2015 年 10 月 1 日至 2017 年 12 月 31 日期间发生的 18-65 岁成人的初次损伤患者。我们比较了两组患者的患者、损伤、治疗和提供者特征,一组患者为长期(≥90 天连续处方类阿片类药物使用),另一组患者为损伤后无阿片类药物使用。
我们共纳入 191130 名符合入选标准的患者,其中 5822 名患者符合长期使用标准。大多数患者损伤轻微,损伤严重程度评分中位数为 1,两组间无差异。几乎所有长期使用阿片类药物的患者在受伤前一年都曾开具过阿片类药物处方(95.3%),而无使用组中这一比例为 31.3%(p < 0.001)。与慢性疼痛、心理健康和物质使用状况相关的合并症在长期使用组中比无使用组更常见。
在这个包含多种类型、主要为轻微损伤的大型队列中,长期使用阿片类药物相对少见,但几乎所有在受伤后长期使用阿片类药物的患者在受伤前都曾使用过阿片类药物。受伤后长期使用阿片类药物可能与受伤前的慢性疼痛和疼痛管理更为密切,而与急性疼痛管理关系不大。