Ashram Waddah Y, Talab Sedrah K, Alotaibi Ruba M, Baarma Reem W, Al Nemer Zainab A, Alshareef Malak A, AlGhamdi Halah H, Alsubhi Reema K
Department of Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
Department of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
Cureus. 2022 Jul 26;14(7):e27301. doi: 10.7759/cureus.27301. eCollection 2022 Jul.
Pericarditis is an inflammatory pericardial disorder that can be caused by several infectious and non-infectious illnesses. Coronavirus disease 2019 (COVID-19) was recently added to the long list of pericarditis causes. As a result, this study aims to look at the incidence of various etiologies of pericarditis, including post-COVID-19 vaccine and risk factors, at King Abdulaziz University Hospital in Jeddah, Saudi Arabia.
Between 2012 and 2022, all male and female patients diagnosed with acute, chronic, or constrictive pericarditis at the King Abdulaziz University Hospital clinic were included in this retrospective study, which took place in June 2022. Data were collected from the hospital's medical records, including the patient's demographic information, pericarditis history, medical history, social background, laboratory tests, Echocardiogram (ECHO) and electrocardiogram (ECG) readings, and medication history. Associations were tested using univariate and bivariate analysis.
Acute pericarditis was diagnosed in 59 (89.1%) patients and the most common symptoms were chest pain and shortness of breath (SOB) followed by fever and cough.Idiopathic pericarditis was the primary etiology 30 (46.9%) with male predominance 25 (55.6%), followed by infections and then cardiac presenting primarily with chest pain 25 (83.3%). In comparison, the most common presentation in females was autoimmune, as seen in eight patients (42.1%). Most patients required aspirin, ibuprofen, and colchicine. Among outcomes, of a total of 64 patients, five died within 30 days. Moreover, four (7.5%) experienced subsequent cardiac tamponades, which was mainly due to malignancy (50%) (p<0.05).
There was a substantial relationship between malignancy and developing morbid complications, with 59 patients out of 64 getting acute pericarditis and the remainder chronic and constrictive pericarditis with idiopathic pericarditis being the leading causes.
心包炎是一种炎症性心包疾病，可由多种感染性和非感染性疾病引起。2019冠状病毒病（COVID-19）最近被列入心包炎病因的长长的名单中。因此，本研究旨在观察沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院心包炎各种病因的发生率，包括COVID-19疫苗接种后病因及危险因素。
2022年6月进行的这项回顾性研究纳入了2012年至2022年间在阿卜杜勒阿齐兹国王大学医院诊所被诊断为急性、慢性或缩窄性心包炎的所有男性和女性患者。数据从医院病历中收集，包括患者的人口统计学信息、心包炎病史、病史、社会背景、实验室检查、超声心动图（ECHO）和心电图（ECG）读数以及用药史。使用单变量和双变量分析进行关联测试。
59例（89.1%）患者被诊断为急性心包炎，最常见的症状是胸痛和呼吸急促（SOB），其次是发热和咳嗽。特发性心包炎是主要病因，有30例（46.9%），男性占优势，为25例（55.6%），其次是感染，然后是主要表现为胸痛的心脏病，有25例（83.3%）。相比之下，女性最常见的表现是自身免疫性疾病，有8例患者（42.1%）。大多数患者需要使用阿司匹林、布洛芬和秋水仙碱。在结果方面，在总共64例患者中，有5例在30天内死亡。此外，4例（7.5%）随后发生了心脏压塞，主要原因是恶性肿瘤（50%）（p<0.05）。
恶性肿瘤与发生病态并发症之间存在密切关系，64例患者中有59例发生急性心包炎，其余为慢性和缩窄性心包炎，特发性心包炎是主要病因。
