Shrivastava Ashish, Raveendran Laxshika, Gau Yung-Tian A
Pediatrics, Children's Hospital of Michigan, Detroit, USA.
Neurology, State University of New York Upstate Medical University, Syracuse, USA.
Cureus. 2022 Jul 25;14(7):e27231. doi: 10.7759/cureus.27231. eCollection 2022 Jul.
Functional neurological disorder (FND) is a constellation of common neurological symptoms without exact organic pathophysiology. The disease arises from aberrant neural computation, and its diagnosis is made upon positive clinical features. FND has emerged as a challenge to healthcare, as clinicians often have limited instructions in assessing it during their career, mainly when there are preexisting organic entities. Here we discuss an inmate whose diagnosis of zolpidem withdrawal seizure is delayed due to co-existing functional mimics and eventually led to an unfavorable outcome. We also review and summarize the current consensus on FND diagnosis and management. Together this report highlights the importance of careful investigation in atypical clinical presentation, with the intent to improve care for both organic and functional neurological patients.
功能性神经障碍（FND）是一组常见的神经症状，没有确切的器质性病理生理学基础。该疾病源于异常的神经计算，其诊断基于阳性临床特征。FND已成为医疗保健领域的一项挑战，因为临床医生在其职业生涯中评估该病时往往指导有限，主要是在存在既往器质性疾病的情况下。在此，我们讨论一名囚犯，其唑吡坦戒断性癫痫发作的诊断因并存的功能性模仿症状而延迟，最终导致了不良后果。我们还回顾并总结了目前关于FND诊断和管理的共识。本报告共同强调了对非典型临床表现进行仔细调查的重要性，旨在改善对器质性和功能性神经疾病患者的护理。
