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中国常用草药的重金属污染评估及人体健康风险评估

Assessment of heavy metals contamination and human health risk assessment of the commonly consumed medicinal herbs in China.

作者信息

Liu Haiping, Tang Jianfeng, Chen Tongjun, Zhu Pingping, Sun Dongdong, Wang Weiyun

机构信息

School of Life Sciences, Anhui Agricultural University, Hefei, 230036, China.

Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China.

出版信息

Environ Sci Pollut Res Int. 2023 Jan;30(3):7345-7357. doi: 10.1007/s11356-022-22647-z. Epub 2022 Aug 30.

Abstract

This study investigates heavy metal contamination of commonly consumed medicinal herbs and human health risks to the Chinese population arising from the consumption of herbs that contain potentially harmful elements. Food safety standards for Chinese residents are becoming stricter, and much work in this field needs to be performed. This study examines Co, Ba, Fe, Cr, Mn, Ni, Zn, As, Cd, Pb, Cu, Be, Sb, and Bi concentrations in four regularly consumed Chinese herb species: Radix Paeoniae Alba (RPA), Radix Angelicae Dahuricae (RAD), Rhizoma Atractylodis Macrocephalae (RAM), and Radix Puerariae (RP). A pollution status examination and evaluation of heavy metals in RPA, RAD, RAM, and RP were performed. The human health risk assessment associated with the intake of potentially harmful elements in herbs was calculated in terms of the estimated daily intake (EDI), the target hazard quotient (THQ), the estimated hazard index (HI), and the lifetime cancer risk (CR). The mean single-factor pollution index (PI) showed that in the RPA, RAD, RAM, and RP samples, approximately 10.0%, 10.0%, 30.0%, and 10.0%, respectively, were polluted by Cd. The present study indicated that the pattern of consumption of the studied herbs in China does not seem to suggest an excessive health hazard associated with any of the toxic elements studied.

摘要

本研究调查了常用药草的重金属污染情况,以及食用含有潜在有害元素的药草给中国人群带来的健康风险。中国居民的食品安全标准日益严格,该领域仍有许多工作需要开展。本研究检测了四种常用中草药白芍(RPA)、白芷(RAD)、白术(RAM)和葛根(RP)中钴、钡、铁、铬、锰、镍、锌、砷、镉、铅、铜、铍、锑和铋的含量。对白芍、白芷、白术和葛根中的重金属污染状况进行了检测和评估。根据估计每日摄入量(EDI)、目标危害商(THQ)、估计危害指数(HI)和终生癌症风险(CR),计算了食用药草中潜在有害元素所带来的人体健康风险评估值。平均单因子污染指数(PI)表明,在白芍、白芷、白术和葛根样本中,镉污染分别约为10.0%、10.0%、30.0%和10.0%。本研究表明,在中国,所研究药草的消费模式似乎并未显示出与所研究的任何有毒元素相关的过度健康危害。

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