Salomatin V V, Lifshits R I
Vopr Med Khim. 1987 Mar-Apr;33(2):73-7.
Binding ability of blood serum albumin was decreased in patients with thermic burns as well as in rats with burns. Loss of this albumin property did not depend on decrease of its content in blood serum; in the patients with burns the decrease in albumin binding ability correlated with development of encephalopathic symptoms. After treatment of blood serum from experimental animals with hemosorbent the blood serum binding ability was distinctly restored in vitro. At the same time, hemosorption did not affect the binding ability of blood plasma in patients with burns. Importance of alterations in binding ability of blood serum albumin for development of acute burns toxemia is discussed.
热烧伤患者以及烧伤大鼠的血清白蛋白结合能力均降低。这种白蛋白特性的丧失并不取决于其血清含量的降低；烧伤患者白蛋白结合能力的降低与脑病症状的发展相关。用血液吸附剂处理实验动物的血清后，血清结合能力在体外明显恢复。同时，血液吸附并不影响烧伤患者血浆的结合能力。本文讨论了血清白蛋白结合能力改变对急性烧伤毒血症发展的重要性。
