Markelov I M, Vikhriev B S, Tupikova Z A, Kuznetsova L A
Vopr Med Khim. 1983 May-Jun;29(3):105-8.
Content of so-called "middle mass molecules" in blood serum of patients with acute burn toxemia was studied by means of gel filtration on Sephadex G-25. Acute burn toxemia was accompanied by accumulation of the molecules in blood serum of the patients with burns; amount of these molecules correlated with a severity of burn trauma. The "middle mass molecules" were effectively eliminated after haemosorption on a charcoal sorbent SKN.2M. The rate of the "middle mass molecules" elimination in haemosorption correlated with improvement of the patients clinical state, with a decrease in symptoms of intoxication; manifestations of acute psychosis were also decreased.
采用Sephadex G - 25凝胶过滤法研究了急性烧伤毒血症患者血清中所谓“中等分子量分子”的含量。急性烧伤毒血症伴有烧伤患者血清中这些分子的蓄积;这些分子的量与烧伤创伤的严重程度相关。“中等分子量分子”在经木炭吸附剂SKN.2M进行血液吸附后被有效清除。血液吸附中“中等分子量分子”的清除率与患者临床状态的改善、中毒症状的减轻相关;急性精神病的表现也有所减轻。