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通过Gm别型分析确定实体器官移植受者体内红细胞抗体的来源。

Gm allotyping to determine the origin of red cell antibodies in recipients of solid organ transplants.

作者信息

Swanson J L, Sastamoinen R M, Steeper T A, Sebring E S

出版信息

Vox Sang. 1987;52(1-2):75-8. doi: 10.1111/j.1423-0410.1987.tb02994.x.

DOI:10.1111/j.1423-0410.1987.tb02994.x
PMID:3604171
Abstract

Alloantibodies of A and B specificity were detected in the serum and on the red cells of 4 non-0 recipients of group 0 solid organ transplants. The antibodies were assumed to be produced by 'passenger' lymphocytes introduced at the time of transplant. Gm allotyping of donor serums, recipient serums and the unexpected antibodies was done. Gm typing was informative in 1 case, when the anti-A1 found in the serum of a liver transplant recipient was shown to be of phenotype Gm(fb) and the Gm phenotype of the recipient to be Gm(axg). Gm allotyping was not informative in the other 3 cases.

摘要

在4例接受0型实体器官移植的非0型受者的血清和红细胞中检测到了具有A和B特异性的同种抗体。这些抗体被认为是移植时引入的“过客”淋巴细胞产生的。对供者血清、受者血清及意外抗体进行了Gm同种异型分型。Gm分型在1例中提供了信息,肝移植受者血清中发现的抗A1显示为Gm(fb)表型,而受者的Gm表型为Gm(axg)。Gm同种异型分型在其他3例中未提供信息。

相似文献

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Gm allotyping to determine the origin of red cell antibodies in recipients of solid organ transplants.通过Gm别型分析确定实体器官移植受者体内红细胞抗体的来源。
Vox Sang. 1987;52(1-2):75-8. doi: 10.1111/j.1423-0410.1987.tb02994.x.
2
Red cell antibodies arising from solid organ transplants.实体器官移植产生的红细胞抗体。
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引用本文的文献

1
Red cell antibody problems in 1000 liver transplants.1000例肝移植中的红细胞抗体问题
Transfusion. 1989 Jun;29(5):396-400. doi: 10.1046/j.1537-2995.1989.29589284137.x.